Fluorene

Fluorene

SCHEMBL19610620

[SiH4].c1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.65
CES1 P23141 2/20 0.59
BCHE P06276 1/20 0.59
KDM4E B2RXH2 2/20 0.58
NPC1 O15118 2/20 0.58
MAPT P10636 2/20 0.58
RAB9A P51151 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
ALDH1A1 P00352 1/20 0.58
LMNA P02545 1/20 0.58
HPGD P15428 1/20 0.58
SRD5A2 P31213 1/20 0.50
PLK4 O00444 1/20 0.48
DAPK3 O43293 1/20 0.48
PIM1 P11309 1/20 0.48
PDGFRA P16234 1/20 0.48
LTK P29376 1/20 0.48
MAP2K2 P36507 1/20 0.48
FLT3 P36888 1/20 0.48
MAPK8 P45983 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorene SCHEMBL27864611 0.97 MAOA (0.62) MAOACES1BCHEKDM4ENPC1
Fluorene SCHEMBL29478468 0.97 MAOA (0.68) MAOACES1BCHEKDM4ENPC1
Fluorene SCHEMBL545861 0.97 MAOA (0.68) MAOACES1BCHEKDM4ENPC1
Fluorene SCHEMBL31388525 0.97 MAOA (0.68) MAOACES1BCHEKDM4ENPC1
Fluorene SCHEMBL8180 0.97 MAOA (0.68) MAOACES1BCHEKDM4ENPC1
Fluorene SCHEMBL29355380 0.97 MAOA (0.68) MAOACES1BCHEKDM4ENPC1
Fluorene SCHEMBL14118022 0.93 MAOA (0.65) MAOACES1BCHEKDM4ENPC1
Fluorene SCHEMBL2432881 0.93 MAOA (0.65) MAOACES1BCHEKDM4ENPC1
Fluorene SCHEMBL10626727 0.93 MAOA (0.65) MAOACES1BCHEKDM4ENPC1
Fluorene SCHEMBL1039293 0.93 MAOA (0.65) MAOACES1BCHEKDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 468 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250072279-A1 METAL COMPLEX WITH FLUORINE SUBSTITUTION Beijing Summer Sprout Technology Co., Ltd. (CN) 2025-02-27 US claimed
US-12167674-B2 Metal complex with fluorine substitution Beijing Summer Sprout Technology Co., Ltd. (CN) 2024-12-10 US claimed
EP-4098716-B1 METAL COMPLEX WITH FLUORINE SUBSTITUTION BEIJING SUMMER SPROUT TECH CO LTD (CN) 2024-08-21 EP claimed
CN-114957309-B Sulfonyl modified silafluorene and dithiophene sulfonyl silafluorene derivative as well as preparation method and application thereof 同济大学 2024-02-23 CN claimed
CN-115746833-A Organic long-afterglow material and preparation method and application thereof 华南师范大学 2023-03-07 CN claimed
US-20230063868-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-03-02 US claimed
EP-4098716-A2 METAL COMPLEX WITH FLUORINE SUBSTITUTION Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-07 EP claimed
CN-113336785-B Aromatic amine compound containing silafluorene and organic electroluminescent device thereof 长春海谱润斯科技股份有限公司 2022-11-11 CN claimed
EP-3623443-B1 METAL COMPLEX WITH FLUORINE SUBSTITUTION BEIJING SUMMER SPROUT TECH CO LTD (CN) 2022-05-18 EP claimed
CN-108598196-B High-weather-resistance solar cell back plate and preparation method thereof 山东冬瑞高新技术开发有限公司 2020-03-27 CN claimed
CN-102060982-A Organic semiconductor material containing naphthalene [1, 2-c: 5, 6-c] di [1, 2, 5] thiadiazole and application thereof UNIV SOUTH CHINA TECH 2011-05-18 CN claimed
CN-102050940-A Organic semiconductor material containing 6-R group- [1, 2, 5] thiazole [3, 4-g] benzotriazole and application thereof UNIV SOUTH CHINA TECH 2011-05-11 CN claimed
CN-101712674-A Alkyl substituted-S,S-dioxo-dibenzothiophene monomer, preparation method and polymer thereof UNIV SOUTH CHINA TECH 2010-05-26 CN claimed
CN-101546887-A Method for realizing laser emission conversion on organic crystal frequency through multi-photon pumping UNIV JILIN 2009-09-30 CN claimed
CN-101405889-A Material for organic electroluminescent element and organic electroluminescent element using same IDEMITSU KOSAN CO (JP) 2009-04-08 CN claimed
CN-100427521-C Novel polyfluorene derivative-polysilicofluorene and method for preparation thereof UNIV FUDAN (CN) 2008-10-22 CN claimed
CN-101255336-A Electroluminescent spectrum-stable blue fluorene-based polymers as well as preparation method and uses thereof UNIV SOUTH CHINA TECH (CN) 2008-09-03 CN claimed
CN-101148495-A Silicon-containing fluorine conjugated polymer and its preparing process and application UNIV SOUTH CHINA TECH (CN) 2008-03-26 CN claimed
CN-1974709-A Electroluminescent conjugated polymer containing polar radical and its application UNIV SOUTH CHINA TECH (CN) 2007-06-06 CN claimed
CN-1654496-A Novel polyfluorene derivative-polysilicofluorene and method for preparation thereof UNIV FUDAN (CN) 2005-08-17 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250072279-A1 METAL COMPLEX WITH FLUORINE SUBSTITUTION AFF4, AFF2, AFF1 MAOA 123/4885CES1 4760/4885BCHE 2246/4885
US-12167674-B2 Metal complex with fluorine substitution AFF4, AFF2, AFF1 MAOA 123/4885CES1 4760/4885BCHE 2246/4885
US-20230063868-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE LEF1, PIEZO1, TMEM109 MAOA 1005/4885CES1 2169/4885BCHE 3067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.