SCHEMBL64820

SCHEMBL64820

NCCC(CCN)CCN

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 2/20 0.33
HRH1 P35367 1/20 0.33
GABBR2 O75899 2/20 0.32
GABBR1 Q9UBS5 2/20 0.32
NFKB1 P19838 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1276021 0.84 NFKB1 (0.40) HRH1NFKB1
SCHEMBL10044829 0.84 NFKB1 (0.40) HRH1NFKB1
SCHEMBL39985 0.82
SCHEMBL1306844 0.82
SCHEMBL16202951 0.82 ALDH1A1 (0.38) GABRR1
SCHEMBL63430 0.82 ALDH1A1 (0.44) GABRR1GABBR2GABBR1
SCHEMBL62359 0.82 CYP3A4 (0.44)
SCHEMBL15894145 0.82
SCHEMBL8642553 0.82 NFKB1 (0.47) NFKB1
SCHEMBL63396 0.82 ALDH1A1 (0.44) GABRR1GABBR2GABBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 356 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120282160-A1 CARBON DIOXIDE AND HYDROGEN SULFIDE ABSORBENTS AND PROCESS FOR THEIR USE CANSOLV TECHNOLOGIES INC. (CA) 2012-11-08 US claimed
EP-2456543-A1 CARBON DIOXIDE AND HYDROGEN SULFIDE ABSORBENTS AND PROCESS FOR THEIR USE Cansolv Technologies Inc. (CA) 2012-05-30 EP claimed
EP-1289637-B1 POLYSULFONAMIDE MATRICES OSMONICS INC (US) 2010-07-21 EP claimed
US-6837996-B2 Porous support matrices; permselective membrane GE OSMONICS, INC. (US) 2005-01-04 US claimed
EP-1289637-A4 POLYSULFONAMIDE MATRICES OSMONICS INC (US) 2004-08-18 EP claimed
US-20030141242-A1 Polysulfonamide matrices OASIS ACQUISITION INC. 2003-07-31 US claimed
EP-1289637-A2 POLYSULFONAMIDE MATRICES OSMONICS, INC. (US) 2003-03-12 EP claimed
WO-2001091873-A2 POLYSULFONAMIDE MATRICES OSMONICS, INC. (US) 2001-12-06 WO claimed
EP-0822835-A1 HYBRID MAGNETIC RESONANCE CONTRAST AGENTS IMARX PHARMACEUTICAL CORP. (US) 1998-02-11 EP claimed
WO-1996032967-A1 HYBRID MAGNETIC RESONANCE CONTRAST AGENTS IMARX PHARMACEUTICAL CORPORATION (US) 1996-10-24 WO claimed
US-5482777-A CROSSLINKED WITH RESIN CONTAINING EPOXY GROUPS, ADDITIONAL BINDER CONTAINING ANIONIC OR CATIONIC GROUPS NIPPON ZEON CO., LTD. (JP) 1996-01-09 US claimed
US-5458127-A Includes a chelated paramagnetic ion IMARX PHARMACEUTICAL CORP. (US) 1995-10-17 US claimed
EP-0435264-B1 Binders for powder and magnetic recording media using same NIPPON ZEON CO (JP) 1995-06-28 EP claimed
US-5407657-A Containing a metal chelate and a free radical nitroxide IMARX THERAPEUTICS, INC. 1995-04-18 US claimed
US-5385719-A Paramagnetic ion chelated to polymers; x-ray and ultrasonic contrast agents, nuclear medicine imaging, radiotherapy, IMARX THERAPEUTICS, INC. 1995-01-31 US claimed
US-5281704-A Polychelant compounds SALUTAR, INC. (US) 1994-01-25 US claimed
WO-1993006148-A1 COPOLYMERS AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING AND IN OTHER APPLICATIONS UNGER EVAN C (US) 1993-04-01 WO claimed
EP-0497926-A1 MULTI-SITE METAL CHELATING AGENTS NYCOMED SALUTAR, INC. (US) 1992-08-12 EP claimed
EP-0435264-A1 Binders for powder and magnetic recording media using same NIPPON ZEON CO., LTD. (JP) 1991-07-03 EP claimed
WO-1991005762-A1 MULTI-SITE METAL CHELATING AGENTS COCKBAIN, JULIAN, RODERICK, MICHAELSON (GB) 1991-05-02 WO claimed