SCHEMBL63430

SCHEMBL63430

NCCC(CCO)CCO

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
TSHR P16473 1/20 0.44
THRB P10828 1/20 0.33
GABRR1 P24046 2/20 0.32
GABBR2 O75899 1/20 0.31
GABBR1 Q9UBS5 1/20 0.31
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL63396 1.00 ALDH1A1 (0.44) ALDH1A1TSHRTHRBGABRR1GABBR2
SCHEMBL5053777 0.88
SCHEMBL27519228 0.85
SCHEMBL3976857 0.85
SCHEMBL64820 0.82 GABRR1 (0.33) GABRR1GABBR2GABBR1
SCHEMBL63049 0.82 THRB (0.44) TSHRTHRBDPP4
SCHEMBL3073650 0.81 TSHR (0.39) ALDH1A1TSHRTHRB
SCHEMBL3068723 0.79 GSR (0.41) ALDH1A1TSHR
SCHEMBL6899876 0.77 DNM1 (0.42) ALDH1A1TSHR
SCHEMBL474837 0.77 DNM1 (0.42) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2330159-B1 ELECTRET AND ELECTROSTATIC INDUCTION CONVERSION DEVICE ASAHI GLASS CO LTD (JP) 2013-04-24 EP disclosed
US-8129869-B2 Electret and electrostatic induction conversion device ASAHI GLASS COMPANY, LIMITED (JP) 2012-03-06 US disclosed
US-20110166299-A1 ELECTRET AND ELECTROSTATIC INDUCTION CONVERSION DEVICE ASAHI GLASS COMPANY, LIMITED 2011-07-07 US disclosed
EP-2330159-A1 ELECTRET AND ELECTROSTATIC INDUCTION CONVERSION DEVICE Asahi Glass Company Limited (JP) 2011-06-08 EP disclosed
US-7862807-B2 Dendrimers as molecular translocators UNIVERSITY OF CALIFORNIA, SAN DIEGO (US) 2011-01-04 US disclosed
US-20100267596-A1 METHOD FOR IMPROVING THE HYDROLYSIS STABILITY OF IONIC LIQUIDS BASE SE (DE) 2010-10-21 US disclosed
US-20080221020-A1 Dendrimers as Molecular Translocators THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-09-11 US disclosed
EP-1545462-A4 DENDRIMERS AS MOLECULAR TRANSLOCATORS UNIV CALIFORNIA (US) 2007-08-08 EP disclosed
US-20060216265-A1 Dendrimers as molecular translocators THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2006-09-28 US disclosed
EP-1545462-A2 DENDRIMERS AS MOLECULAR TRANSLOCATORS The Regents of the University of California (US) 2005-06-29 EP disclosed
WO-2004009665-A2 DENDRIMERS AS MOLECULAR TRANSLOCATORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2004-01-29 WO disclosed
WO-2004009666-A2 DENDRIMERS AS MOLECULAR TRANSLOCATORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2004-01-29 WO disclosed
US-4776886-A Halftone gravure printing inks containing an azo dyestuff BAYER AKTIENGESELLSCHAFT (DE) 1988-10-11 US disclosed
US-4645130-A BALL MILLING WITH ALCOHOL AMERICAN CYANAMID COMPANY (US) 1987-02-24 US disclosed
EP-0184723-A1 Method for treating carbide-based desulfurizing reagents for injection into molten iron CYANAMID CANADA INC. (CA) 1986-06-18 EP disclosed
US-4528031-A Flow promotor for particulate material CYANAMID CANADA, INC. (CA) 1985-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060216265-A1 Dendrimers as molecular translocators SLC29A1, SLC29A2, TSPO ALDH1A1 954/4885TSHR 802/4885THRB 1627/4885
US-20100267596-A1 METHOD FOR IMPROVING THE HYDROLYSIS STABILITY OF IONIC LIQUIDS LIPA, IDE, CEL ALDH1A1 997/4885TSHR 3700/4885THRB 4383/4885
US-20080221020-A1 Dendrimers as Molecular Translocators SLC29A1, SLC29A2, TSPO ALDH1A1 954/4885TSHR 802/4885THRB 1627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.