Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | TP53 | P04637 | 5/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | GFER | P55789 | 1/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.62 |
| ▸ | MMP2 | P08253 | 1/20 | 0.61 |
| ▸ | MMP9 | P14780 | 1/20 | 0.61 |
| ▸ | MMP8 | P22894 | 1/20 | 0.61 |
| ▸ | MMP13 | P45452 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2240398 | 0.91 | MAPT (0.65) | MAPTSMN1; SMN2TP53RAB9ARXFP1 | |
| SCHEMBL14452905 | 0.89 | MAPT (0.64) | MAPTSMN1; SMN2TP53RAB9ARXFP1 | |
| SCHEMBL13254484 | 0.82 | MAPT (0.78) | MAPTSMN1; SMN2TP53RXFP1THRB | |
| SCHEMBL27974618 | 0.82 | RAB9A (0.72) | MAPTSMN1; SMN2TP53RAB9ARXFP1 | |
| SCHEMBL2245512 | 0.81 | MAPT (0.82) | MAPTSMN1; SMN2TP53RAB9ARXFP1 | |
| SCHEMBL16217101 | 0.81 | PTGS2 (0.78) | MAPTSMN1; SMN2TP53RAB9ARXFP1 | |
| SCHEMBL2243746 | 0.81 | MAPT (0.98) | MAPTSMN1; SMN2TP53RAB9ARXFP1 | |
| SCHEMBL29404722 | 0.81 | RAB9A (1.00) | MAPTSMN1; SMN2TP53RAB9ARXFP1 | |
| SCHEMBL1852701 | 0.81 | RAB9A (1.00) | MAPTSMN1; SMN2TP53RAB9ARXFP1 | |
| SCHEMBL19029159 | 0.81 | HDAC6 (0.79) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050260126-A1 | Diagnostic probes and remedies for diseases with accumulation of prion protein, and stains for prion protein | BF RESEARCH INSTITUTE (JP) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050260126-A1 | Diagnostic probes and remedies for diseases with accumulation of prion protein, and stains for prion protein | PRNP, PRPH, PCNP | MAPT 7/4885SMN1; SMN2 214/4885TP53 449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.