SCHEMBL2240398

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6482011	0.91	MAPT (0.71)	MAPTTP53POLBTHRBSMN1; SMN2
	SCHEMBL14452905	0.85	MAPT (0.64)	MAPTTP53POLBTHRBSMN1; SMN2
	SCHEMBL2247467	0.83	RAB9A (0.76)	MAPTTP53HDAC6SMN1; SMN2RXFP1
	SCHEMBL2244601	0.81	NPC1 (0.73)	MAPTTP53HDAC6POLBSMN1; SMN2
	SCHEMBL19029159	0.80	HDAC6 (0.79)	HDAC6
	SCHEMBL13254484	0.79	MAPT (0.78)	MAPTTP53POLBTHRBSMN1; SMN2
	SCHEMBL1675373	0.78	HDAC6 (0.67)	MAPTTP53HDAC6SMN1; SMN2RXFP1
	SCHEMBL2245512	0.78	MAPT (0.82)	MAPTTP53POLBTHRBSMN1; SMN2
	SCHEMBL16217101	0.78	PTGS2 (0.78)	MAPTTP53POLBTHRBSMN1; SMN2
	SCHEMBL2243746	0.78	MAPT (0.98)	MAPTTP53POLBTHRBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.