SCHEMBL6482302

SCHEMBL6482302

O=C1C=C(OC(=O)c2ccc(Cl)c(Cn3cnnn3)c2Cl)CCC1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.33
ALDH1A1 P00352 1/20 0.32
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
KDM4E B2RXH2 1/20 0.30
POLB P06746 1/20 0.30
ALOX12 P18054 1/20 0.30
RECQL P46063 1/20 0.30
HBB P68871 1/20 0.30
HSD17B10 Q99714 1/20 0.30
ATM Q13315 1/20 0.30
RCE1 Q9Y256 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6481108 0.90 MAPK1 (0.36) MAPK1MEN1KMT2ALMNATP53
SCHEMBL6491567 0.87 MEN1 (0.30) MEN1KMT2ACYP1A2CYP2C9
SCHEMBL6489367 0.83 MEN1 (0.31) ALDH1A1MEN1KMT2ACYP1A2CYP2C9
SCHEMBL6480901 0.83 MAPK1 (0.35) MAPK1MEN1KMT2ALMNATP53
SCHEMBL6481163 0.82 POLB (0.33) POLB
SCHEMBL6480767 0.82 MAPK1 (0.34) MAPK1LMNATP53
SCHEMBL6489376 0.81 TP53 (0.43) MAPK1ALDH1A1MEN1KMT2ACYP1A2
SCHEMBL6479768 0.80 P2RX7 (0.33) MAPK1CYP1A2CYP2C9
SCHEMBL6324155 0.79 BUB1 (0.32)
SCHEMBL6482084 0.78 ENPP2 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050090398-A1 Novel tetrazole derivative useful as herbicides YANAGI AKIHIKO (JP) 2005-04-28 US disclosed
EP-1476437-A1 NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES Bayer CropScience AG (DE) 2004-11-17 EP disclosed
WO-2003066607-A1 NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2003-08-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050090398-A1 Novel tetrazole derivative useful as herbicides DDT, TTI1, CYP1A1 MAPK1 2914/4885ALDH1A1 533/4885MEN1 2766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.