Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 4/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 4/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6475194 | 0.83 | LOXL2 (0.42) | CARM1PRMT1LOXL2THRATHRB | |
| SCHEMBL8859981 | 0.80 | FBP1 (0.49) | CARM1PRMT1PDPK1ALDH1A1KDM4E | |
| SCHEMBL6474914 | 0.79 | SMPD3 (0.46) | CARM1PRMT1LOXL2PDPK1ADRB2 | |
| SCHEMBL8684449 | 0.77 | ALDH1A1 (0.41) | CARM1PRMT1LOXL2THRATHRB | |
| SCHEMBL28842595 | 0.75 | LOXL2 (0.67) | CARM1PRMT1LOXL2PDPK1ADRB2 | |
| SCHEMBL1439923 | 0.75 | LOXL2 (0.67) | CARM1PRMT1LOXL2PDPK1ADRB2 | |
| SCHEMBL15194320 | 0.73 | ALDH1A1 (0.46) | CARM1PRMT1PRMT3PRMT6PRMT8 | |
| SCHEMBL18670146 | 0.73 | NPSR1 (0.49) | CARM1PRMT1F2RL1 | |
| SCHEMBL12747050 | 0.72 | PDPK1 (0.59) | CARM1PRMT1LOXL2PDPK1ADRB2 | |
| SCHEMBL30457805 | 0.72 | PDPK1 (0.53) | PDPK1ALDH1A1KDM4EMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6930131-B2 | Aryl substituted 3-ethoxy phenyl trifluoromethane sulfonamides for the treatment of non-insulin dependent diabetes mellitus (NIDDM) | WYETH (US) | 2005-08-16 | — | — | US | disclosed |