Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6483613 | 0.73 | PARP1 (0.47) | PARP1MAPTKMT2AGAA | |
| SCHEMBL6493969 | 0.69 | HRH3 (0.52) | PARP1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20245200 | 0.69 | LMNA (0.84) | LMNARECQLPKMHPGDCYP1A2 | |
| SCHEMBL29031229 | 0.68 | MEN1 (0.77) | LMNARECQLPKMHPGDCYP1A2 | |
| SCHEMBL7946591 | 0.66 | HPGD (0.68) | LMNARECQLPKMHPGDCYP1A2 | |
| SCHEMBL4439444 | 0.65 | PARP1 (1.00) | PARP1 | |
| SCHEMBL3564174 | 0.65 | LMNA (0.64) | LMNARECQLPKMHPGDCYP1A2 | |
| SCHEMBL3559462 | 0.63 | LMNA (0.58) | LMNARECQLPKMHPGDCYP1A2 | |
| SCHEMBL4709087 | 0.63 | MEN1 (0.84) | LMNAPKMHPGDCYP1A2CYP3A4 | |
| SCHEMBL6481336 | 0.62 | PARP1 (0.49) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050159431-A1 | Substituted alkyl uracils and thereof | BAYER HEALTHCARE AG (DE) | 2005-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159431-A1 | Substituted alkyl uracils and thereof | UNG, UMPS, TYMP | PTGDR2 2173/4885LMNA 1689/4885RECQL 121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.