Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PPID | Q08752 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9115091 | 0.92 | MMP8 (0.50) | MMP8ALDH1A1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL9115819 | 0.88 | MMP8 (0.47) | MMP8ALDH1A1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL6131620 | 0.85 | KMT2A (0.45) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL14782773 | 0.84 | L3MBTL1 (0.46) | MMP8ALDH1A1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL7910569 | 0.83 | MMP8 (0.43) | MMP8ALDH1A1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL9116769 | 0.83 | MMP8 (0.57) | MMP8ALDH1A1LMNASMN1; SMN2RECQL | |
| SCHEMBL6938826 | 0.83 | ALDH1A1 (0.47) | MMP8ALDH1A1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL20076113 | 0.82 | MMP8 (0.48) | MMP8ALDH1A1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL8609385 | 0.81 | L3MBTL1 (0.47) | MMP8ALDH1A1SMN1; SMN2RECQLPIN1 | |
| SCHEMBL8068619 | 0.81 | L3MBTL1 (0.47) | ALDH1A1LMNAMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6974802-B2 | Treatment of viral infections using prodrugs of 2′,3-dideoxy,3′-fluoroguanosine | MEDIVIR AB (SE) | 2005-12-13 | — | — | US | disclosed |
| US-6458772-B1 | Prodrugs | MEDIVIR AB (SE) | 2002-10-01 | — | — | US | disclosed |