Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2252181 | 0.71 | ALDH1A1 (0.54) | LMNACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2856946 | 0.71 | C1S (0.38) | LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1007784 | 0.70 | LMNA (0.63) | LMNACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL30905954 | 0.70 | LMNA (0.63) | LMNACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL30032995 | 0.70 | CYP3A4 (0.57) | LMNACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1325881 | 0.70 | CYP3A4 (0.57) | LMNACYP1A2CYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL15910696 | 0.68 | CYP3A4 (0.55) | LMNACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6161689 | 0.68 | DYRK1A (0.31) | — | |
| SCHEMBL17511987 | 0.68 | KDM4E (0.46) | LMNACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29024928 | 0.67 | EGFR (0.47) | LMNACYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6958356-B2 | Guanidine mimics factor Xa inhibitors | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2005-10-25 | — | — | US | disclosed |