Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | THRB | P10828 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6474124 | 0.88 | KDM4E (0.39) | MAPTKDM4ETHRBSMN1; SMN2ALOX12 | |
| SCHEMBL6482640 | 0.86 | MAPT (0.66) | MAPTKDM4ETHRBSMN1; SMN2ALOX12 | |
| SCHEMBL6474490 | 0.81 | MAPT (0.59) | MAPTKDM4ETHRBSMN1; SMN2ALOX12 | |
| SCHEMBL6475808 | 0.79 | KDM4E (0.55) | MAPTKDM4ETHRBSMN1; SMN2ALOX12 | |
| SCHEMBL6484112 | 0.77 | MAPT (0.47) | MAPTKDM4ETHRBSMN1; SMN2ALOX12 | |
| SCHEMBL6473718 | 0.77 | MAPT (0.52) | MAPTKDM4ETHRBSMN1; SMN2ALOX12 | |
| SCHEMBL6473829 | 0.75 | KDM4E (0.52) | MAPTKDM4ETHRBSMN1; SMN2ALOX12 | |
| SCHEMBL9588388 | 0.74 | MAPT (0.67) | MAPTKDM4ETHRBSMN1; SMN2ALOX12 | |
| SCHEMBL6480605 | 0.73 | KDM4E (0.52) | MAPTKDM4ETHRBSMN1; SMN2ALOX12 | |
| SCHEMBL12410797 | 0.72 | MAPT (0.71) | MAPTKDM4ETHRBSMN1; SMN2ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6891038-B2 | Photochromic spiro(indoline)naphthoxazines | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2005-05-10 | — | — | US | disclosed |
| US-20030114669-A1 | Photochromic spiro(indoline)naphthoxazines | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2003-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114669-A1 | Photochromic spiro(indoline)naphthoxazines | NPM1, CRY2, INMT | MAPT 2742/4885KDM4E 1572/4885THRB 3454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.