Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6483916 | 0.88 | MAPT (0.49) | KDM4EMAPTTHRBSMN1; SMN2ALOX12 | |
| SCHEMBL6480605 | 0.87 | KDM4E (0.52) | KDM4EMAPTTHRBSMN1; SMN2ALOX12 | |
| SCHEMBL7262564 | 0.81 | MAPT (0.45) | KDM4EMAPTTHRBSMN1; SMN2ALOX12 | |
| SCHEMBL6475808 | 0.75 | KDM4E (0.55) | KDM4EMAPTTHRBSMN1; SMN2ALOX12 | |
| SCHEMBL6482640 | 0.74 | MAPT (0.66) | KDM4EMAPTTHRBSMN1; SMN2ALOX12 | |
| SCHEMBL1408653 | 0.70 | KDM4E (0.68) | KDM4EMAPTTHRBSMN1; SMN2ALOX12 | |
| SCHEMBL6474490 | 0.69 | MAPT (0.59) | KDM4EMAPTTHRBSMN1; SMN2ALOX12 | |
| SCHEMBL6474400 | 0.68 | KDM4E (0.48) | KDM4EMAPTTHRBSMN1; SMN2ALOX12 | |
| SCHEMBL6474870 | 0.68 | KDM4E (0.47) | KDM4EMAPTTHRBSMN1; SMN2ALOX12 | |
| SCHEMBL6473718 | 0.67 | MAPT (0.52) | KDM4EMAPTTHRBSMN1; SMN2ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6891038-B2 | Photochromic spiro(indoline)naphthoxazines | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2005-05-10 | — | — | US | disclosed |
| US-20030114669-A1 | Photochromic spiro(indoline)naphthoxazines | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2003-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114669-A1 | Photochromic spiro(indoline)naphthoxazines | NPM1, CRY2, INMT | KDM4E 1572/4885MAPT 2742/4885THRB 3454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.