Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.60 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.60 |
| ▸ | CACNB1 | Q02641 | 3/20 | 0.60 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HTR7 | P34969 | 1/20 | 0.58 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976802 | 0.93 | CACNA2D1 (0.66) | ALDH1A1LMNATSHRRAB9AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6482751 | 0.92 | CACNA2D1 (0.65) | ALDH1A1LMNATSHRRAB9AL3MBTL1 | |
| SCHEMBL6484058 | 0.88 | HTR1A (0.63) | ALDH1A1LMNATSHRRAB9AL3MBTL1 | |
| SCHEMBL6546626 | 0.83 | ALDH1A1 (0.65) | ALDH1A1LMNATSHRRAB9AKDM4E | |
| SCHEMBL12781882 | 0.82 | TSHR (0.73) | ALDH1A1LMNATSHRRAB9AL3MBTL1 | |
| SCHEMBL20419343 | 0.82 | TSHR (0.68) | ALDH1A1LMNATSHRRAB9AL3MBTL1 | |
| SCHEMBL10586177 | 0.81 | TSHR (0.71) | ALDH1A1LMNATSHRRAB9AL3MBTL1 | |
| SCHEMBL13979787 | 0.81 | TSHR (0.71) | ALDH1A1LMNATSHRRAB9AL3MBTL1 | |
| SCHEMBL14500742 | 0.81 | TSHR (0.71) | ALDH1A1LMNATSHRRAB9AL3MBTL1 | |
| SCHEMBL8422424 | 0.81 | ALDH1A1 (1.00) | ALDH1A1LMNATSHRRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6894052-B1 | Serotonergic receptor antagonist | RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2005-05-17 | — | — | US | disclosed |
| EP-1000046-B1 | PIPERAZINE DERIVATIVES ACTIVE ON THE LOWER URINARY TRACT | RECORDATI CHEM PHARM (CH) | 2003-11-26 | — | — | EP | disclosed |
| EP-1000046-A1 | PIPERAZINE DERIVATIVES ACTIVE ON THE LOWER URINARY TRACT | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999006383-A1 | PIPERAZINE DERIVATIVES ACTIVE ON THE LOWER URINARY TRACT | RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1999-02-11 | — | — | WO | disclosed |