Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6484201 | 0.88 | ALDH1A1 (0.68) | ALDH1A1MAPTLMNASMN1; SMN2TSHR | |
| SCHEMBL6976802 | 0.86 | CACNA2D1 (0.66) | HTR1AALDH1A1MAPTLMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL6482751 | 0.85 | CACNA2D1 (0.65) | HTR1AALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL6484692 | 0.81 | HTR1A (0.81) | HTR1AALDH1A1MAPTLMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL6971387 | 0.80 | HTR1A (0.79) | HTR1AALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL6936851 | 0.78 | HTR1A (0.69) | HTR1AALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL1580405 | 0.75 | MAPT (0.86) | HTR1AALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL11556531 | 0.74 | MAPK1 (0.69) | HTR1AALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL12781882 | 0.74 | TSHR (0.73) | ALDH1A1LMNAMAPK1SMN1; SMN2TSHR | |
| SCHEMBL20419343 | 0.74 | TSHR (0.68) | ALDH1A1LMNASMN1; SMN2TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6894052-B1 | Serotonergic receptor antagonist | RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2005-05-17 | — | — | US | disclosed |
| EP-1000046-B1 | PIPERAZINE DERIVATIVES ACTIVE ON THE LOWER URINARY TRACT | RECORDATI CHEM PHARM (CH) | 2003-11-26 | — | — | EP | disclosed |