SCHEMBL6485183

SCHEMBL6485183

CNc1ccc2oc3ccccc3c2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.53
KMT2A Q03164 7/20 0.53
NPC1 O15118 6/20 0.53
SMN1; SMN2 Q16637 6/20 0.53
MAPT P10636 6/20 0.53
RAB9A P51151 5/20 0.53
ALDH1A1 P00352 5/20 0.53
HPGD P15428 5/20 0.53
KDM4E B2RXH2 4/20 0.53
AHR P35869 2/20 0.48
GAA P10253 2/20 0.46
NPY5R Q15761 1/20 0.45
CA12 O43570 1/20 0.44
CA9 Q16790 1/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 2/20 0.44
MAOA P21397 2/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.43
LMNA P02545 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20322817 0.89 SMN1; SMN2 (0.58) MEN1KMT2ANPC1SMN1; SMN2MAPT
SCHEMBL30363422 0.84 MAPT (0.57) MEN1KMT2ANPC1SMN1; SMN2MAPT
SCHEMBL2785067 0.84 MAPT (0.57) MEN1KMT2ANPC1SMN1; SMN2MAPT
SCHEMBL23366435 0.82 PLA2G2A (0.45) MEN1KMT2AMAPTKDM4EGAA
SCHEMBL21703740 0.81 ALDH1A1 (0.46) MEN1KMT2ANPC1MAPTRAB9A
SCHEMBL25012052 0.81 MEN1 (0.53) MEN1KMT2ANPC1SMN1; SMN2MAPT
SCHEMBL6482381 0.80 MEN1 (0.50) MEN1KMT2ANPC1SMN1; SMN2MAPT
SCHEMBL18311922 0.79 KMT2A (0.55) MEN1KMT2ANPC1SMN1; SMN2MAPT
SCHEMBL19239181 0.79 MEN1 (0.52) MEN1KMT2ANPC1SMN1; SMN2MAPT
SCHEMBL20181892 0.79 ALDH1A1 (0.52) MEN1KMT2ANPC1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230322656-A1 ORGANIC COMPOUND, AND ELECTRONIC COMPONENT AND ELECTRONIC DEVICE HAVING SAME SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-10-12 US disclosed
US-20230172045-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THEREOF LG DISPLAY CO., LTD. (KR) 2023-06-01 US disclosed
EP-4016659-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2022-06-22 EP disclosed
US-20120074395-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-03-29 US disclosed
US-20120074395-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-03-29 US disclosed
US-20050075332-A1 Tricyclic compounds with antiviral activity WARNER LAMBERT COMPANY 2005-04-07 US disclosed
US-6800656-B2 Tricyclic compounds and method of treating herpes virus WARNER LAMBERT COMPANY 2004-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230322656-A1 ORGANIC COMPOUND, AND ELECTRONIC COMPONENT AND ELECTRONIC DEVICE HAVING SAME PIEZO1, OR10J3, ODC1 MEN1 996/4885KMT2A 2488/4885NPC1 1454/4885
US-20050075332-A1 Tricyclic compounds with antiviral activity HDAC8, CDK8, ZC3HAV1 MEN1 3464/4885KMT2A 770/4885NPC1 2036/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.