Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 17/20 | 0.68 |
| ▸ | IMPDH1 | P20839 | 4/20 | 0.64 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6500618 | 0.89 | IMPDH2 (0.72) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL6485457 | 0.86 | IMPDH2 (0.56) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL6501086 | 0.85 | IMPDH2 (0.77) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL6486483 | 0.84 | IMPDH2 (0.80) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL6493811 | 0.84 | IMPDH2 (0.73) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL6496013 | 0.83 | IMPDH2 (0.74) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL6486128 | 0.83 | IMPDH2 (0.74) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL6495194 | 0.82 | IMPDH2 (0.84) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL1473366 | 0.82 | IMPDH2 (1.00) | IMPDH2IMPDH1AAK1 | |
| Trifluoroacetic Acid SCHEMBL6497386 | 0.82 | IMPDH2 (0.69) | IMPDH2IMPDH1AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867299-B2 | Inosine monophosphate dehydrogenase (IMPDH); use as immunosuppressants, anticancer agents and antiviral agents | HOFFMANN-LA ROCHE INC. (US) | 2005-03-15 | — | — | US | disclosed |