SCHEMBL6486729

SCHEMBL6486729

Cc1c(C(C=C(C(=O)O)C(=O)O)C2CC2)ncc(F)c1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7504894 0.85 NPSR1 (0.36)
SCHEMBL27370729 0.85 P2RX7 (0.31)
SCHEMBL7502117 0.82
SCHEMBL27350827 0.80 S1PR1 (0.33)
SCHEMBL7503443 0.78 FFAR2 (0.34)
SCHEMBL1663001 0.78 IDO1 (0.33)
SCHEMBL5981006 0.74 FFAR2 (0.34)
SCHEMBL27349216 0.72 SLC6A2 (0.40)
SCHEMBL7503245 0.71 P2RX7 (0.33)
SCHEMBL6486723 0.71 SCN2B (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6900224-B2 Antimicrobial quinolones, their compositions and uses THE PROCTER & GAMBLE COMPANY (US) 2005-05-31 US disclosed
US-20040038975-A1 Antimicrobial quinolones, their compositions and uses THE PROCTER & GAMBLE COMPANY 2004-02-26 US disclosed
US-20040029882-A1 Antimicrobial quinolones, their compositions and uses THE PROCTER & GAMBLE CO. 2004-02-12 US disclosed
US-6645981-B2 For therapy of microbial infection THE PROCTER & GAMBLE COMPANY 2003-11-11 US disclosed
US-20030008894-A1 Antimicrobial quinolones, their compositions and uses THE PROCTER & GAMBLE COMPANY 2003-01-09 US disclosed