Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1290145 | 0.84 | NPSR1 (0.37) | IDO1 | |
| SCHEMBL1289954 | 0.81 | IDO1 (0.32) | IDO1NPC1ALOX12RAB9ANCOA1 | |
| SCHEMBL6486729 | 0.78 | — | — | |
| SCHEMBL1290278 | 0.73 | IDO1 (0.33) | IDO1NPC1ALOX12RAB9ANCOA1 | |
| SCHEMBL7106369 | 0.67 | IMPDH2 (0.32) | IDO1 | |
| SCHEMBL12502479 | 0.64 | ADRA1A (0.33) | IDO1 | |
| SCHEMBL20285913 | 0.63 | TDO2 (0.33) | — | |
| SCHEMBL25262008 | 0.63 | NOS3 (0.32) | — | |
| SCHEMBL31283250 | 0.62 | AXL (0.31) | — | |
| SCHEMBL1290211 | 0.61 | ACVRL1 (0.39) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047487-A1 | 2-PYRIDONE ANTIMICROBIAL COMPOSITIONS | EVOLVA SA (CH) | 2012-04-12 | — | — | WO | disclosed |