Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6497679 | 0.94 | MCL1 (0.40) | MCL1PLA2G2ADCTPP1 | |
| SCHEMBL6490596 | 0.93 | MCL1 (0.38) | MCL1PLA2G2ACYSLTR2CYSLTR1PDE3B | |
| SCHEMBL6491102 | 0.88 | PDE3B (0.43) | MCL1PLA2G2ACYSLTR2CYSLTR1PDE3B | |
| SCHEMBL6499460 | 0.88 | CYSLTR2 (0.35) | MCL1PLA2G2ACYSLTR2CYSLTR1PDE3B | |
| SCHEMBL6502915 | 0.87 | SMN1; SMN2 (0.44) | MCL1PLA2G2ACYSLTR2CYSLTR1PDE3B | |
| SCHEMBL6488241 | 0.87 | MCL1 (0.43) | MCL1PLA2G2ACYSLTR2CYSLTR1PDE3B | |
| SCHEMBL6499832 | 0.86 | PLA2G2A (0.42) | MCL1PLA2G2ACYSLTR2CYSLTR1PDE3B | |
| SCHEMBL6491512 | 0.86 | MCL1 (0.41) | MCL1PLA2G2ACYSLTR2CYSLTR1PDE3B | |
| SCHEMBL6488675 | 0.86 | PLA2G2A (0.41) | MCL1PLA2G2ACYSLTR2CYSLTR1PDE3B | |
| SCHEMBL6487942 | 0.85 | MCL1 (0.42) | MCL1PLA2G2ACYSLTR2CYSLTR1PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | MCL1 806/4885PLA2G2A 4801/4885CYSLTR2 2679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.