Dimethylamine

Dimethylamine

SCHEMBL6486963

CCc1ccncc1.CNC

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.52
KMT2A Q03164 3/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
LOXL2 Q9Y4K0 2/20 0.46
MAPT P10636 2/20 0.46
HPGD P15428 1/20 0.46
ALDH1A1 P00352 5/20 0.44
CYP3A4 P08684 2/20 0.44
CYP2C19 P33261 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TP53 P04637 2/20 0.43
NPC1 O15118 1/20 0.43
LMNA P02545 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
TSHR P16473 1/20 0.42
NOS3 P29474 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylamine SCHEMBL6486307 0.97 RAB9A (0.50) RAB9AKMT2AL3MBTL1LOXL2MAPT
SCHEMBL14208 0.92
SCHEMBL27348535 0.89
Bromide SCHEMBL27763500 0.89 LOXL2 (0.50) RAB9AKMT2AL3MBTL1LOXL2MAPT
Ammonia Solution, Strong SCHEMBL3452396 0.89
Hydrochloric Acid SCHEMBL11424635 0.89 LOXL2 (0.50) RAB9AKMT2AL3MBTL1LOXL2MAPT
Hydrochloric Acid SCHEMBL11079689 0.89
Bromide SCHEMBL9131563 0.89
SCHEMBL31540632 0.89
Iodide SCHEMBL4057600 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4402843-A Viscosity index improvers with dispersant properties prepared by reaction of lithiated hydrogenated copolymers with 4-substituted aminopyridines PHILLIPS PETROLEUM COMPANY (US) 1983-09-06 US claimed
US-6867299-B2 Inosine monophosphate dehydrogenase (IMPDH); use as immunosuppressants, anticancer agents and antiviral agents HOFFMANN-LA ROCHE INC. (US) 2005-03-15 US disclosed
US-20020052513-A1 Oxamide IMPDH inhibitors HOFFMANN-LA ROCHE INC. 2002-05-02 US disclosed
EP-1127883-A2 Oxamides as IMPDH inhibitors F. HOFFMANN-LA ROCHE AG (CH) 2001-08-29 EP disclosed
US-4546176-A 7-Carboxymethoxyphenylacetamido-3-cephem derivatives and antibacterial preparations containing the same EISAI CO., LTD. (JP) 1985-10-08 US disclosed
US-4402843-A Viscosity index improvers with dispersant properties prepared by reaction of lithiated hydrogenated copolymers with 4-substituted aminopyridines PHILLIPS PETROLEUM COMPANY (US) 1983-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020052513-A1 Oxamide IMPDH inhibitors IMPDH1, IMPDH2, IMPA1 RAB9A 3252/4885KMT2A 3733/4885L3MBTL1 2494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.