⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27857517 | 0.82 | — | — | |
| SCHEMBL21442584 | 0.79 | — | — | |
| SCHEMBL22416394 | 0.77 | PRMT3 (0.35) | — | |
| SCHEMBL8279894 | 0.77 | — | — | |
| SCHEMBL19554001 | 0.75 | DNM1 (0.38) | — | |
| SCHEMBL17624895 | 0.75 | TP53 (0.37) | — | |
| SCHEMBL9877397 | 0.74 | DNM1 (0.30) | — | |
| SCHEMBL2682823 | 0.74 | DNM1 (0.30) | — | |
| SCHEMBL4506753 | 0.71 | MGLL (0.36) | — | |
| SCHEMBL3865761 | 0.70 | DNM1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3625219-A1 | PROCESS FOR PREPARING SUBSTITUTED IMIDAZOLYLCARBOXYAMIDES | Bayer Aktiengesellschaft (DE) | 2020-03-25 | — | — | EP | claimed |
| US-6939866-B2 | Quinazoline derivatives | ASTRAZENECA AB (SE) | 2005-09-06 | — | — | US | claimed |
| US-4235981-A | MODIFIED CYCLOPENTADIENE-MALEIC ANHYDRIDE COPOLYMER IN REACTIVE SOLVENT | NIPPON OIL CO., LTD. (JP) | 1980-11-25 | — | — | US | claimed |
| US-10583141-B2 | N-substituted hydroxamic acids with carbon-based leaving groups as efficient HNO donors and uses thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2020-03-10 | — | — | US | disclosed |
| US-20180185367-A1 | N-SUBSTITUTED HYDROXAMIC ACIDS WITH CARBON-BASED LEAVING GROUPS AS EFFICIENT HNO DONORS AND USES THEREOF | NATIONAL SCIENCE FOUNDATION | 2018-07-05 | — | — | US | disclosed |
| US-20180155827-A1 | Synthesis of Metal Nitride Thin Films Materials using Hydrazine Derivatives | APPLIED MATERIALS, INC. | 2018-06-07 | — | — | US | disclosed |
| US-8456396-B2 | Liquid crystal display device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2013-06-04 | — | — | US | disclosed |
| US-6316482-B1 | FOR THERAPY AND PROPHYLAXIS OF HYPERTENSION, HEART FAILURE, RENAL INSUFFICIENCY, EDEMA, ASCITES, VASOPRESSIN PARASECRETION SYNDROME, HEPATOCIRRHOSIS, HYPONATREMIA, HYPOKALEMIA, DIABETIC, CIRCULATION DISORDER, CEREBROVASCULAR DISEASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-13 | — | — | US | disclosed |
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| US-6207693-B1 | Benzamide derivatives having a vasopressin antagonistic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |
| WO-1998024771-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-11 | — | — | WO | disclosed |
| EP-0832061-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-01 | — | — | EP | disclosed |
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |
| EP-0685489-A2 | Tripeptide antithrombotic agents | ELI LILLY AND COMPANY (US) | 1995-12-06 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |
| US-4885299-A | TREATMENT OF ENERGY INSUFFICIENCY AND CEREBRAL AGING | ADIR ET CIE (FR) | 1989-12-05 | — | — | US | disclosed |
| US-4859700-A | 2-(2,3-dihydro-2-oxo-3-benzofuranyl)acetic acid compounds having antihypoxic and nootropic effects | ADIR ET CIE (FR) | 1989-08-22 | — | — | US | disclosed |
| US-3985757-A | ANTIINFLAMMATORY AGENTS AND TRANQUILIZERS | E. R. SQUIBB & SONS, INC. (US) | 1976-10-12 | — | — | US | disclosed |