Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6486783 | 0.91 | SIGMAR1 (0.37) | HRH3SIGMAR1SMN1; SMN2 | |
| SCHEMBL6485505 | 0.87 | HRH3 (0.32) | HRH3 | |
| SCHEMBL6485116 | 0.85 | HRH3 (0.39) | HRH3SIGMAR1MAPTSMN1; SMN2 | |
| SCHEMBL2750006 | 0.85 | HRH3 (0.50) | HRH3SIGMAR1MAPTCXCR4CYP1A2 | |
| SCHEMBL42822 | 0.80 | HRH3 (0.55) | HRH3SIGMAR1MAPTCXCR4CYP1A2 | |
| SCHEMBL6593644 | 0.80 | HRH3 (0.42) | HRH3SIGMAR1MAPTCYP1A2MAPK1 | |
| SCHEMBL22915903 | 0.79 | — | — | |
| SCHEMBL19273693 | 0.79 | — | — | |
| SCHEMBL5950060 | 0.79 | HRH3 (0.39) | HRH3MAPTCXCR4CYP1A2MAPK1 | |
| SCHEMBL1580535 | 0.79 | HRH3 (0.39) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6962911-B2 | Pyrrolopyrimidinone derivatives, process of preparation and use | SK CHEMICALS CO., LTD. (KR) | 2005-11-08 | — | — | US | disclosed |
| EP-1257553-B1 | PYRROLOPYRIMIDINONE DERIVATIVES, PROCESS OF PREPARATION AND USE | SK CHEMICALS CO LTD (KR) | 2004-05-26 | — | — | EP | disclosed |