Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43407 | 0.95 | HRH3 (0.46) | HRH3CARM1PRMT6PRMT8MAPT | |
| SCHEMBL42959 | 0.92 | HRH3 (0.50) | HRH3CARM1PRMT6PRMT8MAPT | |
| SCHEMBL2750006 | 0.90 | HRH3 (0.50) | HRH3CARM1PRMT6PRMT8MAPT | |
| SCHEMBL42822 | 0.84 | HRH3 (0.55) | HRH3CARM1PRMT6PRMT8MAPT | |
| SCHEMBL1489852 | 0.83 | DRD2 (0.34) | HRH3CARM1PRMT6PRMT8SIGMAR1 | |
| SCHEMBL2919539 | 0.83 | ALOX15 (0.52) | HRH3CARM1PRMT6PRMT8L3MBTL1 | |
| SCHEMBL6485505 | 0.83 | HRH3 (0.32) | HRH3 | |
| SCHEMBL1448524 | 0.83 | KMT2A (0.41) | HRH3MAPTALDH1A1POLBL3MBTL1 | |
| SCHEMBL42493 | 0.82 | HRH3 (0.59) | HRH3MAPTALDH1A1POLBCYP1A2 | |
| SCHEMBL9432306 | 0.81 | KEAP1 (0.48) | HRH3ALDH1A1POLBCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |