Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 7/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 5/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503445 | 0.93 | AGTR1 (0.46) | AGTR1BCL2MCL1ALOX5APPTGER1 | |
| SCHEMBL6498787 | 0.89 | BCL2 (0.40) | AGTR1BCL2MCL1ALOX5APMAPT | |
| SCHEMBL6488562 | 0.89 | AGTR1 (0.41) | AGTR1BCL2MCL1AGTR2 | |
| SCHEMBL6488564 | 0.88 | AGTR1 (0.44) | AGTR1BCL2MCL1AGTR2 | |
| SCHEMBL6487753 | 0.86 | PIK3C2B (0.40) | AGTR1BCL2MCL1ALOX5APMAPT | |
| SCHEMBL6498230 | 0.84 | ALOX5AP (0.38) | AGTR1BCL2MCL1ALOX5APMAPT | |
| SCHEMBL6488244 | 0.83 | LMNA (0.40) | BCL2MCL1ALOX5APMAPTPTGER1 | |
| SCHEMBL6501134 | 0.82 | BCL2 (0.47) | BCL2MCL1 | |
| SCHEMBL6500043 | 0.81 | BCL2 (0.45) | AGTR1BCL2MCL1AGTR2 | |
| SCHEMBL6488163 | 0.81 | PIK3C2B (0.37) | AGTR1BCL2MCL1ALOX5APMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | AGTR1 2045/4885PTGDR2 3318/4885BCL2 774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.