Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.38 |
| ▸ | HTR7 | P34969 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6493552 | 0.99 | DRD3 (0.41) | DRD3HRH2HRH1GAASIGMAR1 | |
| SCHEMBL6487284 | 0.76 | KDM4E (0.41) | HRH2HRH1SIGMAR1ALDH1A1 | |
| SCHEMBL6496563 | 0.76 | ALDH1A1 (0.56) | HRH2HRH1GAAALDH1A1 | |
| SCHEMBL6485200 | 0.75 | KDM4E (0.41) | HRH2HRH1SIGMAR1ALDH1A1 | |
| SCHEMBL22521105 | 0.72 | HRH2 (0.56) | DRD3HRH2HRH1HTR7HTR1A | |
| SCHEMBL4330983 | 0.72 | ACHE (0.46) | ALDH1A1 | |
| SCHEMBL18476170 | 0.71 | HRH2 (0.54) | DRD3HRH2HRH1 | |
| SCHEMBL24773181 | 0.70 | HRH2 (0.53) | DRD3HRH2HRH1GAASIGMAR1 | |
| SCHEMBL27969328 | 0.70 | SIGMAR1 (0.48) | DRD3HRH2HRH1GAASIGMAR1 | |
| SCHEMBL13612751 | 0.69 | GAA (0.48) | DRD3HRH2HRH1GAABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6861432-B2 | Piperazine derivatives that destabilize androgen receptors | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-03-01 | — | — | US | disclosed |