SCHEMBL6488261

SCHEMBL6488261

c1ccc([C@@H]2CO2)nc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30316733 1.00
SCHEMBL531613 1.00
SCHEMBL29240535 1.00
SCHEMBL12533533 0.98 TSHR (0.43)
SCHEMBL22263381 0.86 ALDH1A1 (0.38)
SCHEMBL31361158 0.85 ALDH1A1 (0.37)
SCHEMBL9065034 0.85 HRH3 (0.38)
Hydrochloric Acid SCHEMBL28248572 0.83 HRH3 (0.37)
SCHEMBL31111388 0.83 HRH3 (0.43)
SCHEMBL15321440 0.79 DRD2 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118265691-A Cyclohexylbeta-hydroxyalkylamines and their medical use 阿托基公司 2024-06-28 CN disclosed
US-20050043358-A1 Aminoalcohol derivatives and their use as beta 3 adrenergic agonists FUJISAWA PHARMACEUTICAL CO. LTD. (JP) 2005-02-24 US disclosed
US-20020143034-A1 Aminoalcohol derivatives and their use as beta 3 adrenergic agonists FUJISAWA PHARMACEUTICAL CO. LTD. (JP) 2002-10-03 US disclosed