O-Coumaric Acid

O-Coumaric Acid

SCHEMBL64885

O=C(O)/C=C/c1ccccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 2/20 1.00
CA1 P00915 1/20 1.00
CA2 P00918 1/20 1.00
CA4 P22748 1/20 1.00
JUN P05412 1/20 0.73
NFE2L2 Q16236 1/20 0.73
MAPT P10636 4/20 0.68
LMNA P02545 1/20 0.68
BCHE P06276 1/20 0.63
GUSB P08236 1/20 0.63
CHRNA7 P36544 3/20 0.58
TRPA1 O75762 1/20 0.57
MAPK1 P28482 2/20 0.56
HDAC3 O15379 1/20 0.56
TNKS O95271 1/20 0.56
HDAC4 P56524 1/20 0.56
HDAC1 Q13547 1/20 0.56
HCAR2 Q8TDS4 1/20 0.56
HDAC7 Q8WUI4 1/20 0.56
HDAC2 Q92769 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Coumaric Acid SCHEMBL64886 1.00 NFKB1 (1.00) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL29353381 1.00 NFKB1 (1.00) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL892006 1.00 NFKB1 (1.00) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL29367602 1.00 NFKB1 (1.00) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL29368085 1.00 NFKB1 (1.00) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL1221495 0.98 NFKB1 (0.96) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL8719132 0.98 NFKB1 (0.96) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL8719129 0.98 NFKB1 (0.96) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL28048519 0.98 NFKB1 (0.96) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL28048517 0.98 NFKB1 (0.96) NFKB1CA1CA2CA4JUN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10737 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070479-A Ultrasonic indicating device and method for monitoring ultrasonic treatment JP实验室股份有限公司 2026-05-19 CN claimed
US-20260132413-A1 AROGENATE DEHYDROGENASE POLYNUCLEOTIDES, POLYPEPTIDES AND METHODS OF USING THE SAME WISCONSIN ALUMNI RES FOUNDATION (US) 2026-05-14 US claimed
EP-3869192-B1 METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE HUMAN METABOLOMICS INST INC (CN) 2026-05-13 EP claimed
US-20260107958-A1 BEE NUTRITION APIX BIOSCIENCES NV aka APIX BIOSCIENCE (BE) 2026-04-23 US claimed
US-20260101892-A1 METHOD TO INHIBIT PROLIFERATION OF A PHYTOPATHOGEN ON PLANTS AND COMPOSITIONS USED FOR THIS PURPOSE CYSBIO APS (DK) 2026-04-16 US claimed
US-20260083866-A1 COMPOSITIONS TARGETING ENDOTHELIAL CELLS AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2026-03-26 US claimed
US-20260083141-A1 EDIBLE TREATMENT COMPOSITION FOR SHELF-LIFE EXTENSION OF MUSHROOMS NAVORK INNOVATIONS PRIVATE LTD (IN) 2026-03-26 US claimed
EP-4712938-A1 SKIN CARE COMPOSITION COMPRISING HYDROXYCINNAMIC ACID AND NIACINAMIDE DERIVATIVE The Procter & Gamble Company (US) 2026-03-25 EP claimed
US-12564190-B2 Biobased herbicide enhancer agent and method for using the same FYTEKO SA (BE) 2026-03-03 US claimed
US-20260049175-A1 POLYESTER DERIVED FROM BIOMASS NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2026-02-19 US claimed
EP-0117741-A2 Process for producing L-histidine by fermentation and microorganisms for use therein KYOWA HAKKO KOGYO CO., LTD. (JP) 1984-09-05 EP claimed
US-4468478-A Polyurethanes prepared from polyoxyalkylenes containing alkaline catalyst residues chelated with benzoic acid derivatives BASF WYANDOTTE CORPORATION (US) 1984-08-28 US claimed
EP-0039472-B1 RADIATION-CROSSLINKABLE POLYESTERS AND POLYESTERETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-08-15 EP claimed
US-4426448-A PREPARARATION OF CAFFEIC ACID KIKKOMAN CORPORATION (JP) 1984-01-17 US claimed
US-4410626-A Process for the production of 7α-methoxycephalosporin derivatives YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1983-10-18 US claimed
US-4370416-A CULTIVATION OF ASPERGILLUS OR BOTRYTIS KIKKOMAN CORPORATION (JP) 1983-01-25 US claimed
US-4302199-A Hair dyeing method THE PROCTER & GAMBLE COMPANY (US) 1981-11-24 US claimed
EP-0039472-A1 Radiation-crosslinkable polyesters and polyesterethers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-11-11 EP claimed
US-4284710-A FROM DIEPOXIDE AND AROMATIC UNSATURATED DICARBOXYLIC ACID OR HYDROXY ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-08-18 US claimed
US-3998851-A PREPARATION OF COUMARINS UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-12-21 US claimed