O-Coumaric Acid

O-Coumaric Acid

SCHEMBL29367602

O=C(O)C=Cc1ccccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 2/20 1.00
CA1 P00915 1/20 1.00
CA2 P00918 1/20 1.00
CA4 P22748 1/20 1.00
JUN P05412 1/20 0.73
NFE2L2 Q16236 1/20 0.73
MAPT P10636 4/20 0.68
LMNA P02545 1/20 0.68
BCHE P06276 1/20 0.63
GUSB P08236 1/20 0.63
CHRNA7 P36544 3/20 0.58
TRPA1 O75762 1/20 0.57
MAPK1 P28482 2/20 0.56
HDAC3 O15379 1/20 0.56
TNKS O95271 1/20 0.56
HDAC4 P56524 1/20 0.56
HDAC1 Q13547 1/20 0.56
HCAR2 Q8TDS4 1/20 0.56
HDAC7 Q8WUI4 1/20 0.56
HDAC2 Q92769 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Coumaric Acid SCHEMBL64885 1.00 NFKB1 (1.00) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL64886 1.00 NFKB1 (1.00) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL29353381 1.00 NFKB1 (1.00) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL892006 1.00 NFKB1 (1.00) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL29368085 1.00 NFKB1 (1.00) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL1221495 0.98 NFKB1 (0.96) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL8719132 0.98 NFKB1 (0.96) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL8719129 0.98 NFKB1 (0.96) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL28048519 0.98 NFKB1 (0.96) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL28048517 0.98 NFKB1 (0.96) NFKB1CA1CA2CA4JUN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026088186-A1 FERMENTED AND DEHYDRATED ALOE GEL PRODUCT AND PROCESS FOR THE PREPARATION THEREOF YOSHAY IDO MOSHE (IL) 2026-04-30 WO claimed
WO-2025090061-A1 ULTRASONIC INDICATOR DEVICE AND METHOD FOR MONITORING ULTRASONICATION JP LABORATORIES, INC. (US) 2025-05-01 WO claimed
CN-118584013-B Method for simultaneously determining contents of various components in turbidity-resolving, stagnation-resolving and arthralgia-removing formula based on UHPLC-QqQ-MS/MS technology 福建中医药大学 2025-04-08 CN claimed
CN-119735523-A Food flavoring compound N-phenylacrylamide acid and preparation method and application thereof 华南理工大学 2025-04-01 CN claimed
CN-119710940-A Small tower-base monocrystalline silicon alkali polishing additive and application method thereof 合肥中聚和成电子材料有限公司 2025-03-28 CN claimed
EP-4476349-A2 METHODS FOR PRODUCTION OF ANIMAL-FREE HONEY AND MILK SUBSTITUTES Sifotek, As (NO) 2024-12-18 EP claimed
WO-2024243545-A1 COMPOSITIONS TARGETING ENDOTHELIAL CELLS AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-11-28 WO claimed
CN-118880340-A Green corrosion inhibitor for cooling water system 苏州热工研究院有限公司 2024-11-01 CN claimed
CN-118584013-A Method for simultaneously determining contents of various components in turbidity-resolving, stagnation-resolving and arthralgia-removing formula based on UHPLC-QqQ-MS/MS technology 福建中医药大学 2024-09-03 CN claimed
CN-117810455-B Graphite negative electrode material with strong cohesiveness and preparation method thereof 深圳市华明胜科技有限公司 2024-05-24 CN claimed
CN-117843923-A Cinnamic acid intrinsic flame-retardant epoxy resin and preparation method thereof 江苏领瑞新材料科技有限公司 2024-04-09 CN claimed
CN-117810455-A Graphite negative electrode material with strong cohesiveness and preparation method thereof 深圳市华明胜科技有限公司 2024-04-02 CN claimed
WO-2023141256-A2 METHODS FOR PRODUCTION OF ANIMAL-FREE HONEY AND MILK SUBSTITUTES Sifotek, AS (NO) 2023-07-27 WO claimed
EP-3432890-B1 PRODUCT, IN PARTICULAR NUTRITIONAL SUPPLEMENT, ANIMAL FEED, FOODSTUFF, DRUG, COSMETIC AND/OR ANIMAL FEED SUPPLEMENT FOR SUPPLYING AT LEAST ONE MOLECULE THAT BONDS TO A VITAMIN D RECEPTOR, AND METHOD FOR THE PRODUCTION THEREOF BUETER BERND (CH) 2023-07-12 EP claimed
CN-113603986-B Preparation method of high-strength weather-resistant PVC cable material 湖南惟楚线缆高分子材料有限公司 2022-10-21 CN claimed
CN-113994946-A Application of o-hydroxy cinnamic acid in removing harmful benthic diatom 广东海洋大学 2022-02-01 CN claimed
US-20260146356-A1 RHENIUM-COBALT ALLOY COMPOSITION AND PROCESS FOR EFFECTIVE METAL ELECTRODEPOSITION IN 3D-INTEGRATION MACDERMID ENTHONE INC. (US) 2026-05-28 US disclosed
EP-4743076-A2 SYNTHETIC BI-FUNCTIONAL DEGRADERS OF INTEGRINS The Board of Trustees of the Leland Stanford Junior University (US) 2026-05-20 EP disclosed
CN-113994946-A Application of o-hydroxy cinnamic acid in removing harmful benthic diatom 广东海洋大学 2022-02-01 CN disclosed
CN-113994946-A Application of o-hydroxy cinnamic acid in removing harmful benthic diatom 广东海洋大学 2022-02-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146356-A1 RHENIUM-COBALT ALLOY COMPOSITION AND PROCESS FOR EFFECTIVE METAL ELECTRODEPOSITION IN 3D-INTEGRATION NRAS, CA3, RAC3 NFKB1 4426/4885CA1 67/4885CA2 368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.