O-Coumaric Acid

O-Coumaric Acid

SCHEMBL64886

O=C(O)C=Cc1ccccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 2/20 1.00
CA1 P00915 1/20 1.00
CA2 P00918 1/20 1.00
CA4 P22748 1/20 1.00
JUN P05412 1/20 0.73
NFE2L2 Q16236 1/20 0.73
MAPT P10636 4/20 0.68
LMNA P02545 1/20 0.68
BCHE P06276 1/20 0.63
GUSB P08236 1/20 0.63
CHRNA7 P36544 3/20 0.58
TRPA1 O75762 1/20 0.57
MAPK1 P28482 2/20 0.56
HDAC3 O15379 1/20 0.56
TNKS O95271 1/20 0.56
HDAC4 P56524 1/20 0.56
HDAC1 Q13547 1/20 0.56
HCAR2 Q8TDS4 1/20 0.56
HDAC7 Q8WUI4 1/20 0.56
HDAC2 Q92769 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Coumaric Acid SCHEMBL64885 1.00 NFKB1 (1.00) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL29353381 1.00 NFKB1 (1.00) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL892006 1.00 NFKB1 (1.00) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL29367602 1.00 NFKB1 (1.00) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL29368085 1.00 NFKB1 (1.00) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL1221495 0.98 NFKB1 (0.96) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL8719132 0.98 NFKB1 (0.96) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL8719129 0.98 NFKB1 (0.96) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL28048519 0.98 NFKB1 (0.96) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL28048517 0.98 NFKB1 (0.96) NFKB1CA1CA2CA4JUN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2501 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070479-A Ultrasonic indicating device and method for monitoring ultrasonic treatment JP实验室股份有限公司 2026-05-19 CN claimed
EP-3869192-B1 METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE HUMAN METABOLOMICS INST INC (CN) 2026-05-13 EP claimed
US-20260083866-A1 COMPOSITIONS TARGETING ENDOTHELIAL CELLS AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2026-03-26 US claimed
US-12497636-B2 Recombinant Saccharomyces cerevisiae cells for cannabinoid production NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-12-16 US claimed
US-20250258146-A1 QUANTITATIVE DETECTION METHOD OF MULTIPLE METABOLITES IN BIOLOGICAL SAMPLE AND METABOLIC CHIP HUMAN METABOLOMICS INSTITUTE INC. (CN) 2025-08-14 US claimed
EP-3494396-B1 CHEMILUMINESCENT AND FLUORESCENT SUBSTRATE PADS AND USES THEREOF PIERCE BIOTECHNOLOGY INC (US) 2025-06-11 EP claimed
CN-120114523-A Lipase inhibitor with specific structure and preparation method and application thereof 中国海洋大学 2025-06-10 CN claimed
CN-119985745-A Detection method for micromolecular phenolic substances and application thereof 北京中医药大学 2025-05-13 CN claimed
WO-2025090061-A1 ULTRASONIC INDICATOR DEVICE AND METHOD FOR MONITORING ULTRASONICATION JP LABORATORIES, INC. (US) 2025-05-01 WO claimed
WO-2025075611-A1 ULTRASONIC INDICATOR BASED ON EMULSION FORMATION JP LABORATORIES, INC. (US) 2025-04-10 WO claimed
WO-1995017534-A1 METALLIC SCREEN MATERIAL HAVING A STRAND OR FIBRE STRUCTURE, AND METHOD FOR MANUFACTURING SUCH A MATERIAL STORK SCREENS B.V. (NL) 1995-06-29 WO claimed
EP-0623604-A2 Oxa(Thia)-diazol-oxyphenylacrylates as pesticides BAYER AG (DE) 1994-11-09 EP claimed
EP-0620918-A1 CARBON DIOXIDE DETECTOR. JOHNSON & JOHNSON PROFESSIONAL (GB) 1994-10-26 EP claimed
WO-1993014399-A1 CARBON DIOXIDE DETECTOR JOHNSON & JOHNSON PROFESSIONAL PRODUCTS LTD. (GB) 1993-07-22 WO claimed
EP-0350971-A1 Process for producing L-glutamic acid by fermentation and mutant microorganisms for use therein KYOWA HAKKO KOGYO CO., LTD. (JP) 1990-01-17 EP claimed
EP-0117741-A2 Process for producing L-histidine by fermentation and microorganisms for use therein KYOWA HAKKO KOGYO CO., LTD. (JP) 1984-09-05 EP claimed
EP-0117740-A2 Process for producing L-glutamic acid by fermentation and mutant microorganisms for use therein KYOWA HAKKO KOGYO CO., LTD. (JP) 1984-09-05 EP claimed
US-4468478-A Polyurethanes prepared from polyoxyalkylenes containing alkaline catalyst residues chelated with benzoic acid derivatives BASF WYANDOTTE CORPORATION (US) 1984-08-28 US claimed
US-4302199-A Hair dyeing method THE PROCTER & GAMBLE COMPANY (US) 1981-11-24 US claimed
US-3998851-A PREPARATION OF COUMARINS UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-12-21 US claimed