SCHEMBL648865

SCHEMBL648865

CCCCOC(=O)CC(=O)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.53
TDP1 Q9NUW8 4/20 0.53
L3MBTL1 Q9Y468 3/20 0.53
KMT2A Q03164 4/20 0.52
MAPK1 P28482 4/20 0.52
MEN1 O00255 3/20 0.52
CYP3A4 P08684 3/20 0.52
HPGD P15428 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
KDM4E B2RXH2 2/20 0.52
MAPT P10636 1/20 0.52
ALOX15 P16050 1/20 0.52
CES1 P23141 1/20 0.52
LMNA P02545 4/20 0.50
RAB9A P51151 2/20 0.48
ALDH1A1 P00352 3/20 0.48
TP53 P04637 1/20 0.47
NPC1 O15118 1/20 0.47
MMP1 P03956 1/20 0.47
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1487522 0.94 TSHR (0.55) TSHRTDP1MAPK1CYP3A4SMN1; SMN2
SCHEMBL1907940 0.94 TSHR (0.55) TSHRTDP1MAPK1CYP3A4SMN1; SMN2
SCHEMBL23466791 0.92 TDP1 (0.49) TSHRTDP1L3MBTL1KMT2AMAPK1
SCHEMBL2375373 0.90 LMNA (0.62) TDP1KMT2AMAPK1MEN1CYP3A4
SCHEMBL29549033 0.90 TDP1 (0.60) TDP1L3MBTL1KMT2AMAPK1MEN1
SCHEMBL1318009 0.86 FAAH (0.55) TSHRTDP1MAPK1CYP3A4SMN1; SMN2
SCHEMBL7629094 0.83 MMP1 (0.61) TSHRTDP1L3MBTL1KMT2AMAPK1
SCHEMBL124577 0.82 KMT2A (0.59) TDP1L3MBTL1KMT2AMAPK1MEN1
SCHEMBL27260848 0.82 KMT2A (0.50) TSHRTDP1KMT2AMAPK1MEN1
SCHEMBL28740463 0.81 KMT2A (0.53) TSHRTDP1KMT2AMAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107876092-B Application of titanium catalyst with cyclic structure as reaction catalyst for synthesizing benzyl carbonate or diphenyl carbonate by ester exchange 华东理工大学 2023-01-10 CN claimed
CN-107876092-A The high stability titanium catalyst of ester exchange carbonate synthesis benzene methyl and diphenyl carbonate 华东理工大学 2018-04-06 CN claimed
CN-107417719-A A kind of titanium chelate catalyst for being used for carbonate synthesis benzene methyl and diphenyl carbonate 华东理工大学 2017-12-01 CN claimed
CN-101657759-B Alkali-developable photosensitive resin composition and beta-diketone ADEKA CORP 2012-07-25 CN claimed
US-11891537-B2 Triphenylphosphine-containing coatings with enhanced adhesion to unprimed surfaces SHEBOYGAN PAINT COMPANY (US) 2024-02-06 US disclosed
CN-107417719-B Application of titanium chelate as reaction catalyst for synthesizing benzyl carbonate or diphenyl carbonate by ester exchange 华东理工大学 2022-11-25 CN disclosed
US-20220325110-A1 TRIPHENYLPHOSPHINE-CONTAINING COATINGS WITH ENHANCED ADHESION TO UNPRIMED SURFACES SHEBOYGAN PAINT COMPANY 2022-10-13 US disclosed
WO-2022212457-A1 TRIPHENYLPHOSPHINE-CONTAINING COATINGS WITH ENHANCED ADHESION TO UNPRIMED SURFACES SHEBOYGAN PAINT COMPANY (US) 2022-10-06 WO disclosed
CN-113087880-B Polyester and preparation method thereof 中国科学院长春应用化学研究所 2022-03-29 CN disclosed
CN-107418281-B Putty composition and repair coating method using same 关西涂料株式会社 2021-08-03 CN disclosed
CN-113087880-A Polyester and preparation method thereof 中国科学院长春应用化学研究所 2021-07-09 CN disclosed
CN-109054138-A High-hardness wear-resistant cable sheath material and preparation method thereof 合肥帧讯低温科技有限公司 2018-12-21 CN disclosed
US-5969015-A FOR ENHANCING PERFORMANCE PROPERTIES OF LUBRICANTS, HYDRAULIC FLUIDS OR METAL PROCESSING FLUIDS WITCO VINYL ADDITIVES GMBH (DE) 1999-10-19 US disclosed
EP-0776346-B1 STABILISED PVDC-CONTAINING PVC WITCO VINYL ADDITIVES GMBH (DE) 1999-06-02 EP disclosed
US-5726234-A Stabilized PVDC-containing PVC CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-03-10 US disclosed
US-5648413-A Stabilizer for chlorine-containing polymers, process for the preparation thereof and chlorine-containing polymer composition MIZUSAWA INDUSTRIAL CHEMICALS, INC. (JP) 1997-07-15 US disclosed
EP-0776346-A1 STABILISED PVDC-CONTAINING PVC Ciba SC Holding AG (CH) 1997-06-04 EP disclosed
EP-0725109-A1 Stabilizer for chlorine-containing polymers, process for the preparation thereof and chlorine-containing polymer composition MIZUSAWA INDUSTRIAL CHEMICALS, LTD. (JP) 1996-08-07 EP disclosed
WO-1996005247-A1 STABILISED PVDC-CONTAINING PVC CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1996-02-22 WO disclosed
US-3993437-A Process for the dyeing of polyamide fibers with sulphur dyestuffs CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-11-23 US disclosed