Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 3/20 | 0.61 |
| ▸ | CDK1 | P06493 | 3/20 | 0.61 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.61 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.61 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.61 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.61 |
| ▸ | GSK3A | P49840 | 1/20 | 0.61 |
| ▸ | GSK3B | P49841 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | KDM4A | O75164 | 1/20 | 0.50 |
| ▸ | KDM5A | P29375 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2289799 | 0.87 | DAO (0.47) | CCNB2CDK1CCNB1CCNB3CDK5 | |
| SCHEMBL2284708 | 0.84 | CCNB2 (0.61) | CCNB2CDK1CCNB1CCNB3CDK5 | |
| SCHEMBL8602417 | 0.76 | ADORA2A (0.59) | CCNB2CDK1CCNB1CCNB3CDK5 | |
| SCHEMBL23207344 | 0.76 | QPCT (0.55) | NPC1RAB9ADAOATAD2KDM4E | |
| SCHEMBL29912855 | 0.76 | CCNB2 (1.00) | CCNB2CDK1CCNB1CCNB3CDK5 | |
| SCHEMBL490933 | 0.76 | CCNB2 (1.00) | CCNB2CDK1CCNB1CCNB3CDK5 | |
| SCHEMBL14976218 | 0.75 | CCNB2 (0.49) | CCNB2CDK1CCNB1CCNB3CDK5 | |
| SCHEMBL18446120 | 0.74 | ITK (0.63) | KDM4EHPGDGAAALDH1A1 | |
| SCHEMBL20252218 | 0.73 | DAO (0.38) | CCNB2CDK1CCNB1CCNB3CDK5 | |
| SCHEMBL19976237 | 0.73 | CDK8 (0.52) | CDK1CDK5GSK3BRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107778495-B | Cadmium metal organic framework complex and preparation method thereof | 宁波大学 | 2021-01-12 | — | — | CN | disclosed |
| CN-107778495-A | A kind of cadmium metal organic frame complex and preparation method thereof | 宁波大学 | 2018-03-09 | — | — | CN | disclosed |
| WO-2008022467-A1 | 2-SUBSTITUTED AZAIN DOLES AND 2 SUBSTITUTED THIENOPYRROLES, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2008-02-28 | — | — | WO | disclosed |
| US-20050014942-A1 | Transforming growth factor inhibitor; controllign cell differentiation, cell proliferation | NIPPON SHINYAKU CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
| EP-1452525-A1 | AMIDE DERIVATIVES AND DRUGS | Nippon Shinyaku Co., Ltd. (JP) | 2004-09-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014942-A1 | Transforming growth factor inhibitor; controllign cell differentiation, cell proliferation | TGFBR1, TGFBR2, TGFB1 | CCNB2 1062/4885CDK1 822/4885CCNB1 423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.