Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 4/20 | 0.61 |
| ▸ | CDK1 | P06493 | 4/20 | 0.61 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.61 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.61 |
| ▸ | GSK3A | P49840 | 3/20 | 0.61 |
| ▸ | GSK3B | P49841 | 3/20 | 0.61 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.61 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.61 |
| ▸ | CTSV | O60911 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6489332 | 0.84 | CCNB2 (0.61) | CCNB2CDK1CCNB1CCNB3GSK3A | |
| SCHEMBL2289799 | 0.83 | DAO (0.47) | CCNB2CDK1CCNB1CCNB3GSK3A | |
| SCHEMBL29913067 | 0.76 | CCNB2 (1.00) | CCNB2CDK1CCNB1CCNB3GSK3A | |
| SCHEMBL491029 | 0.76 | CCNB2 (1.00) | CCNB2CDK1CCNB1CCNB3GSK3A | |
| SCHEMBL23207344 | 0.75 | QPCT (0.55) | KDM4ENPC1RAB9ASMN1; SMN2DAO | |
| SCHEMBL25248466 | 0.74 | DAO (0.53) | CCNB2CDK1CCNB1CCNB3GSK3A | |
| SCHEMBL7892114 | 0.73 | RIPK1 (0.71) | CCNB2CDK1CCNB1CCNB3GSK3A | |
| SCHEMBL22102705 | 0.72 | NR4A2 (0.42) | CCNB2CDK1CCNB1CCNB3NPC1 | |
| SCHEMBL2061664 | 0.72 | RAB9A (0.71) | CTSVCTSLKDM4ENPC1RAB9A | |
| SCHEMBL29496847 | 0.72 | RAB9A (0.71) | CTSVCTSLKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207732-A1 | AZAINDOLE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207732-A1 | AZAINDOLE DERIVATIVES | AZI2, ABL1, RET | CCNB2 265/4885CDK1 32/4885CCNB1 214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.