Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | DPYD | Q12882 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39008 | 0.89 | NFE2L2 (0.60) | NFE2L2TRPA1MEN1KMT2AMAOB | |
| SCHEMBL19031413 | 0.89 | NFE2L2 (0.60) | NFE2L2TRPA1MEN1KMT2AMAOB | |
| SCHEMBL30130338 | 0.89 | NFE2L2 (0.60) | NFE2L2TRPA1MEN1KMT2AMAOB | |
| SCHEMBL28399996 | 0.89 | NFE2L2 (0.60) | NFE2L2TRPA1MEN1KMT2AMAOB | |
| SCHEMBL29567711 | 0.89 | NFE2L2 (0.60) | NFE2L2TRPA1MEN1KMT2AMAOB | |
| SCHEMBL15242 | 0.87 | NFE2L2 (0.58) | NFE2L2TRPA1MEN1KMT2AMAOB | |
| SCHEMBL11899749 | 0.87 | NFE2L2 (0.58) | NFE2L2TRPA1MEN1KMT2AMAOB | |
| SCHEMBL10381282 | 0.85 | MAOA (0.45) | NFE2L2TRPA1LMNAMEN1THRB | |
| SCHEMBL24385991 | 0.85 | LMNA (0.62) | NFE2L2TRPA1LMNAMEN1THRB | |
| SCHEMBL192400 | 0.85 | LMNA (0.62) | NFE2L2TRPA1LMNAMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050096491-A1 | Aromatic methylidene compound, methylstyryl compound for producing the same, production method therefor, and organic electroluminescent element | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2005-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050096491-A1 | Aromatic methylidene compound, methylstyryl compound for producing the same, production method therefor, and organic electroluminescent element | OR51E2, CYP4F11, ACAD11 | NFE2L2 52/4885TRPA1 443/4885LMNA 3310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.