Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491011 | 0.91 | PRMT5 (0.43) | DHODHPARP1PRMT5WDR77PTGES | |
| SCHEMBL7197499 | 0.89 | DHODH (0.55) | DHODHPARP1 | |
| SCHEMBL6501625 | 0.89 | PTGES (0.40) | DHODHPARP1PRMT5WDR77PTGES | |
| SCHEMBL6498457 | 0.87 | KDM4E (0.43) | DHODHPARP1PTGESALDH1A1LMNA | |
| SCHEMBL6499860 | 0.86 | PRMT5 (0.47) | PRMT5WDR77LMNACYP1A2CYP3A4 | |
| SCHEMBL6498657 | 0.79 | ALDH1A1 (0.40) | PRMT5WDR77ALDH1A1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL6492977 | 0.74 | ALDH1A1 (0.46) | ALDH1A1LMNAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL31123658 | 0.73 | ALDH1A1 (0.60) | ALDH1A1LMNAKDM4EMAPTHPGD | |
| SCHEMBL29262118 | 0.72 | DHODH (0.43) | DHODHPARP1HPGD | |
| SCHEMBL30001450 | 0.72 | DHODH (0.43) | DHODHPARP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | DHODH 759/4885PARP1 3898/4885PRMT5 1076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.