Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | VDR | P11473 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6501198 | 0.93 | NR4A2 (0.48) | CYSLTR1SMPD1NR4A2DHODHPPARG | |
| SCHEMBL6489915 | 0.90 | NR4A2 (0.46) | CYSLTR1DCTPP1NR4A2PPARGMRGPRX4 | |
| SCHEMBL6490528 | 0.89 | DCTPP1 (0.42) | CYSLTR1DCTPP1VDRNR1H2NR1H3 | |
| SCHEMBL6498198 | 0.87 | DCTPP1 (0.47) | DCTPP1NR1H2MCL1LMNASMN1; SMN2 | |
| SCHEMBL6488028 | 0.86 | AGTR1 (0.40) | DCTPP1VDRDHODHMRGPRX4SMN1; SMN2 | |
| SCHEMBL6501562 | 0.84 | NR4A2 (0.57) | NR4A2PPARGMRGPRX4RXRA | |
| SCHEMBL6496471 | 0.83 | DCTPP1 (0.37) | DCTPP1PPARGMCL1SMN1; SMN2 | |
| SCHEMBL6492529 | 0.83 | PIK3C2B (0.38) | DCTPP1PPARGMCL1SMN1; SMN2 | |
| SCHEMBL6489346 | 0.82 | MRGPRX4 (0.46) | NR4A2PPARGMRGPRX4NR1H4SMN1; SMN2 | |
| SCHEMBL6498787 | 0.82 | BCL2 (0.40) | DCTPP1NR4A2PPARGMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | CYSLTR1 2525/4885DCTPP1 1534/4885SMPD1 570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.