Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28504677 | 0.81 | MCL1 (0.44) | MCL1DPP4 | |
| SCHEMBL6219908 | 0.78 | MEN1 (0.38) | MCL1HTTHSD17B10 | |
| SCHEMBL5079020 | 0.76 | MCL1 (0.52) | MCL1 | |
| SCHEMBL1405183 | 0.75 | LMNA (0.48) | MCL1HSD17B10DPP4 | |
| SCHEMBL4943847 | 0.75 | LMNA (0.48) | MCL1HSD17B10DPP4 | |
| SCHEMBL5759921 | 0.74 | NPC1 (0.35) | HSD17B10 | |
| SCHEMBL1070893 | 0.74 | MCL1 (0.38) | MCL1 | |
| SCHEMBL1070889 | 0.74 | MCL1 (0.48) | MCL1 | |
| SCHEMBL9653268 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL5796983 | 0.73 | LMNA (0.46) | MCL1HSD17B10DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184177-A1 | AROMATIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 甫康（上海）健康科技有限责任公司 | 2022-09-09 | — | — | WO | disclosed |
| EP-3066095-A1 | SUBSTITUTED 1,2,4-TRIAZINE-3,5-DIONES AND THE USE THEREOF AS CHYMASE INHIBITORS | Bayer Pharma Aktiengesellschaft (DE) | 2016-09-14 | — | — | EP | disclosed |
| WO-2015067650-A1 | SUBSTITUTED 1,2,4-TRIAZINE-3,5-DIONES AND THE USE THEREOF AS CHYMASE INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-05-14 | — | — | WO | disclosed |
| US-6951857-B2 | Interleukins; cytokines; for treating eosinophil-dependent inflammatory disease/bronchial asthma | FREYNE EDDY JEAN EDGARD | 2005-10-04 | — | — | US | disclosed |
| US-5830893-A | Treatment of equine protozoan myeloencephalitis using triazinediones | MORTAR & PESTLE VETERINARY PHARMACY, INC. (US) | 1998-11-03 | — | — | US | disclosed |
| US-4631278-A | Anti-protozoal α-aryl-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)-benzeneacetonitrile derivatives, pharmaceutical compositions, and method of use therefor | JANSSEN PHARMACEUTICA N.V. (BE) | 1986-12-23 | — | — | US | disclosed |
| EP-0029719-B1 | VULCANIZABLE RUBBER COMPOSITIONS INHIBITED FROM PREMATURE VULCANIZATION BY METHYLENE THIOETHERS, AND NOVEL METHYLENE THIOETHERS | MONSANTO COMPANY (US) | 1983-02-16 | — | — | EP | disclosed |
| US-4342705-A | CONTAINING CARBONYL OR CYANO FUNCTIONAL GROUPS, USEFUL AS VULCANIZATION INHIBITORS | MONSANTO COMPANY (US) | 1982-08-03 | — | — | US | disclosed |
| EP-0029719-A1 | Vulcanizable rubber compositions inhibited from premature vulcanization by methylene thioethers, and novel methylene thioethers | MONSANTO COMPANY (US) | 1981-06-03 | — | — | EP | disclosed |
| US-4271050-A | Vulcanizable rubber compositions inhibited from premature vulcanization by methylene thioethers | MONSANTO COMPANY (US) | 1981-06-02 | — | — | US | disclosed |