Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SUMO3 | P55854 | 1/20 | 0.45 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.45 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6216135 | 0.83 | TDO2 (0.47) | ALDH1A1SUMO3SUMO2SUMO1KDM4E | |
| SCHEMBL16596951 | 0.76 | ALDH1A1 (0.63) | PIK3CDALDH1A1TSHRKCNH2 | |
| SCHEMBL23958344 | 0.74 | PIK3CD (0.45) | PIK3CDALDH1A1 | |
| SCHEMBL754019 | 0.74 | PIK3CD (0.70) | PIK3CDALDH1A1KDM4E | |
| SCHEMBL10296670 | 0.74 | PIK3CD (0.63) | PIK3CDALDH1A1KDM4E | |
| SCHEMBL16591381 | 0.72 | PIK3CD (0.52) | PIK3CDALDH1A1TSHR | |
| SCHEMBL18923549 | 0.72 | PIK3CD (0.52) | PIK3CDALDH1A1 | |
| SCHEMBL6214167 | 0.71 | — | — | |
| SCHEMBL10296669 | 0.69 | PIK3CD (0.47) | PIK3CD | |
| SCHEMBL16596955 | 0.68 | PIK3CD (0.57) | PIK3CDALDH1A1TSHRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6921764-B2 | Thieno-pyrimidin-4-one AMPA antagonists | PFIZER INC. (US) | 2005-07-26 | — | — | US | disclosed |