SCHEMBL6489710

SCHEMBL6489710

CCOC(=O)c1ccc(Cl)c(OCCn2nnc(SC)n2)c1Cl

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.41
MAPT P10636 3/20 0.41
HPGD P15428 3/20 0.41
TDP1 Q9NUW8 2/20 0.39
KDM4E B2RXH2 2/20 0.38
BAZ2B Q9UIF8 1/20 0.37
BAZ2A Q9UIF9 1/20 0.37
LMNA P02545 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
GPR55 Q9Y2T6 1/20 0.37
TEAD2 Q15562 1/20 0.37
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
MAPK1 P28482 2/20 0.36
USP2 O75604 1/20 0.36
HTT P42858 1/20 0.36
POLB P06746 2/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6495117 0.88 LMNA (0.34) ALDH1A1MAPTHPGDLMNASMN1; SMN2
SCHEMBL6483187 0.88 MEN1 (0.35) ALDH1A1MAPTHPGDKDM4ELMNA
SCHEMBL6482410 0.88 BAZ2B (0.39) ALDH1A1MAPTHPGDKDM4EBAZ2B
SCHEMBL6492924 0.80 LMNA (0.39) ALDH1A1MAPTHPGDTDP1LMNA
SCHEMBL587539 0.79 BAZ2B (0.39) ALDH1A1MAPTKDM4EBAZ2BBAZ2A
SCHEMBL6303905 0.77 TEAD2 (0.38) ALDH1A1MAPTHPGDTDP1KDM4E
SCHEMBL6494876 0.77 MAPK1 (0.42) ALDH1A1HPGDBAZ2BBAZ2ALMNA
SCHEMBL587378 0.76 GAA (0.45) ALDH1A1HPGDKDM4EBAZ2BBAZ2A
SCHEMBL6492362 0.76 SMN1; SMN2 (0.38) ALDH1A1MAPTHPGDLMNASMN1; SMN2
SCHEMBL6480978 0.76 LMNA (0.38) ALDH1A1MAPTHPGDKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050090398-A1 Novel tetrazole derivative useful as herbicides YANAGI AKIHIKO (JP) 2005-04-28 US disclosed
EP-1476437-A1 NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES Bayer CropScience AG (DE) 2004-11-17 EP disclosed
WO-2003066607-A1 NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2003-08-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050090398-A1 Novel tetrazole derivative useful as herbicides DDT, TTI1, CYP1A1 ALDH1A1 533/4885MAPT 3026/4885HPGD 4216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.