Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 5/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490023 | 1.00 | KMO (0.69) | KMOKDM4EHIF1ATDP1 | |
| SCHEMBL7797582 | 0.81 | KMO (1.00) | KMO | |
| SCHEMBL7797593 | 0.81 | KMO (1.00) | KMO | |
| SCHEMBL7797590 | 0.81 | KMO (1.00) | KMO | |
| Hydrochloric Acid SCHEMBL8057534 | 0.80 | KMO (1.00) | KMO | |
| Hydrochloric Acid SCHEMBL8393037 | 0.80 | KMO (1.00) | KMO | |
| Hydrochloric Acid SCHEMBL7908769 | 0.80 | KMO (1.00) | KMO | |
| Bromide SCHEMBL6485753 | 0.78 | KMO (0.50) | KMOKDM4EHIF1ATDP1 | |
| Bromide SCHEMBL6479497 | 0.78 | KMO (0.50) | KMOKDM4EHIF1ATDP1 | |
| SCHEMBL7791510 | 0.75 | KMO (0.68) | KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949541-B2 | Substituted piperidines, medicaments containing these compounds, and methods for the production thereof | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2005-09-27 | — | — | US | disclosed |
| US-20030212057-A1 | Substituted piperidines, medicaments containing these compounds, and methods for the production thereof | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212057-A1 | Substituted piperidines, medicaments containing these compounds, and methods for the production thereof | CALCA, CALCRL, P2RY1 | KMO 3092/4885KDM4E 4675/4885HIF1A 837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.