Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 5/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797582 | 1.00 | KMO (1.00) | KMOTSHRSLC6A4SLC6A3 | |
| SCHEMBL7797593 | 1.00 | KMO (1.00) | KMOTSHRSLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL8057534 | 0.98 | KMO (1.00) | KMOTSHRSLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL7908769 | 0.98 | KMO (1.00) | KMOTSHRSLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL8393037 | 0.98 | KMO (1.00) | KMOTSHRSLC6A4SLC6A3 | |
| SCHEMBL19642672 | 0.84 | KMO (0.75) | KMOTSHRSLC6A4SLC6A3 | |
| SCHEMBL6490028 | 0.81 | KMO (0.69) | KMO | |
| SCHEMBL6490023 | 0.81 | KMO (0.69) | KMO | |
| SCHEMBL3670421 | 0.81 | KMO (1.00) | KMOTSHRSLC6A4SLC6A3 | |
| SCHEMBL4386002 | 0.81 | KMO (1.00) | KMOTSHRSLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010008947-A1 | 2-AMINO-4-PHENYL-4-OXO-BUTYRIC ACID DERIVATIVES | VARASI MARIO (IT) | 2001-07-19 | — | — | US | disclosed |
| EP-0662948-B1 | 2-AMINO-4-PHENYL-4-OXO-BUTYRIC ACID DERIVATIVES WITH KYNURENINASE AND/OR KYNURENINE-3-HYDROXYLASE INHIBITING ACTIVITY | PHARMACIA & UPJOHN SPA (IT) | 1998-10-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010008947-A1 | 2-AMINO-4-PHENYL-4-OXO-BUTYRIC ACID DERIVATIVES | KYNU, KMO, ABAT | KMO 2/4885TSHR 4661/4885SLC6A4 468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.