Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 6/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL41864 | 0.93 | HCAR2 (0.53) | HCAR2FFAR1HPGDLTB4RLTB4R2 | |
| SCHEMBL10907558 | 0.93 | HCAR2 (0.53) | HCAR2FFAR1HPGDLTB4RLTB4R2 | |
| SCHEMBL14258939 | 0.84 | TSHR (0.41) | HCAR2HPGDLTB4RLTB4R2ALDH1A1 | |
| SCHEMBL28116999 | 0.83 | LMNA (0.46) | HCAR2FFAR1ALDH1A1ELANEOPRM1 | |
| Ethylene Glycol SCHEMBL2515273 | 0.83 | HCAR2 (0.53) | HCAR2FFAR1LTB4RLTB4R2ALDH1A1 | |
| SCHEMBL10204727 | 0.82 | HCAR2 (0.49) | HCAR2FFAR1HPGDLTB4RLTB4R2 | |
| SCHEMBL9159588 | 0.81 | HCAR2 (0.44) | HCAR2FFAR1HPGDLTB4RLTB4R2 | |
| SCHEMBL8088686 | 0.80 | HCAR2 (0.61) | HCAR2FFAR1ALDH1A1TP53HSD17B10 | |
| SCHEMBL17511150 | 0.80 | ALDH1A1 (0.42) | HCAR2HPGDALDH1A1ELANECYP3A4 | |
| SCHEMBL29351716 | 0.80 | HCAR2 (0.44) | HCAR2HPGDLTB4RLTB4R2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6852820-B2 | Method for preparing acrylic copolymer materials suitable for ophthalmic devices | NIDEK CO., LTD. (JP) | 2005-02-08 | — | — | US | disclosed |
| EP-1035142-A1 | Acrylic copolymer materials suitable for ophthalmic devices | Nidek Co., Ltd. (JP) | 2000-09-13 | — | — | EP | disclosed |