Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | SMO | Q99835 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MTTP | P55157 | 3/20 | 0.42 |
| ▸ | APOB | P04114 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6792614 | 0.92 | SMO (0.55) | TRPV1SMOMAPTLMNATDP1 | |
| SCHEMBL6492227 | 0.88 | SMO (0.49) | TRPV1SMOMTTPAPOBSMN1; SMN2 | |
| SCHEMBL6803739 | 0.87 | SMO (0.48) | TRPV1SMOMAPTLMNAMTTP | |
| SCHEMBL6504077 | 0.86 | SMO (0.48) | TRPV1SMOMTTPAPOBNR3C1 | |
| SCHEMBL7084419 | 0.86 | MAPT (0.50) | TRPV1SMOMAPTLMNATDP1 | |
| SCHEMBL6490835 | 0.85 | SMO (0.50) | TRPV1SMOMTTPAPOBNR3C1 | |
| SCHEMBL6497088 | 0.84 | HTR2C (0.51) | TRPV1SMOMTTPAPOBNPC1 | |
| SCHEMBL6804647 | 0.83 | TRPV1 (0.45) | TRPV1SMOMTTPAPOBNR3C1 | |
| SCHEMBL6804655 | 0.83 | TRPV1 (0.45) | TRPV1SMOMTTPAPOBNR3C1 | |
| SCHEMBL6488178 | 0.81 | SMO (0.52) | TRPV1SMOMTTPAPOBNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6864268-B2 | β3 adrenergic receptor agonists | PFIZER INC. (US) | 2005-03-08 | — | — | US | disclosed |
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | TRPV1 2245/4885SMO 2580/4885MAPT 4202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.