Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3677264 | 0.84 | FFAR1 (0.66) | FFAR1FFAR4PPARDMMEMMEL1 | |
| SCHEMBL3670702 | 0.83 | FFAR1 (0.76) | FFAR1FFAR4RXRA | |
| SCHEMBL8984877 | 0.83 | FFAR1 (0.57) | FFAR1FFAR4ALOX5TP53MDM2 | |
| SCHEMBL7725124 | 0.82 | FFAR1 (0.58) | FFAR1FFAR4TP53MDM2PLA2G4A | |
| SCHEMBL347209 | 0.81 | FFAR4 (0.61) | FFAR1FFAR4ALOX5PLA2G4AKDM4E | |
| SCHEMBL30488611 | 0.80 | FFAR1 (0.55) | FFAR1FFAR4ALOX5PLA2G4ATRPV1 | |
| SCHEMBL21222812 | 0.80 | FFAR1 (0.55) | FFAR1FFAR4ALOX5PLA2G4ATRPV1 | |
| Hydrochloric Acid SCHEMBL3225386 | 0.80 | FFAR4 (0.59) | FFAR1FFAR4ALOX5PLA2G4AKDM4E | |
| SCHEMBL5296276 | 0.79 | FFAR1 (0.55) | FFAR1FFAR4TP53MDM2PPARD | |
| SCHEMBL17537957 | 0.78 | POLB (0.54) | FFAR1FFAR4ALOX5PPARDPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6972296-B2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC. (US) | 2005-12-06 | — | — | US | disclosed |