SCHEMBL7725124

SCHEMBL7725124

COc1ccc(CCC(=O)O)cc1-c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 11/20 0.58
TP53 P04637 3/20 0.56
MDM2 Q00987 3/20 0.56
FFAR4 Q5NUL3 7/20 0.53
PLA2G4A P47712 1/20 0.49
MME P08473 1/20 0.49
MMEL1 Q495T6 1/20 0.49
RXRA P19793 1/20 0.49
PTPN1 P18031 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8984877 0.89 FFAR1 (0.57) FFAR1TP53MDM2FFAR4RXRA
SCHEMBL3683148 0.87 FFAR4 (0.61) FFAR1TP53MDM2FFAR4
SCHEMBL28454360 0.85 GAA (0.62)
SCHEMBL7735506 0.84 PTGDR2 (0.63) FFAR1TP53MDM2FFAR4
SCHEMBL27752603 0.84 ALOX5 (0.51) FFAR1TP53MDM2FFAR4PTPN1
SCHEMBL20613278 0.84 PPARA (0.64) FFAR1TP53MDM2FFAR4
SCHEMBL3677264 0.84 FFAR1 (0.66) FFAR1FFAR4MMEMMEL1RXRA
SCHEMBL7735763 0.83 PTPN1 (0.54) FFAR1PTPN1
SCHEMBL7236351 0.83 FFAR1 (0.65) FFAR1FFAR4MMEMMEL1
SCHEMBL3670702 0.83 FFAR1 (0.76) FFAR1FFAR4RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376546-B1 ANTIALLERGENS ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-04-23 US disclosed
EP-1024130-A1 BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-08-02 EP disclosed