Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6480268 | 0.98 | ALDH1A1 (0.30) | ALDH1A1MAPK1HTT | |
| SCHEMBL6491373 | 0.89 | — | — | |
| SCHEMBL6481157 | 0.85 | POLB (0.33) | — | |
| SCHEMBL6480542 | 0.84 | KMT2A (0.34) | ALDH1A1MAPK1HTT | |
| SCHEMBL6479315 | 0.84 | POLB (0.33) | — | |
| SCHEMBL6482294 | 0.84 | POLB (0.33) | — | |
| SCHEMBL6491370 | 0.83 | — | — | |
| SCHEMBL6479779 | 0.82 | MAPK1 (0.33) | ALDH1A1MAPK1HTT | |
| SCHEMBL6492543 | 0.82 | — | — | |
| SCHEMBL6450192 | 0.81 | ALDH1A1 (0.30) | ALDH1A1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050222247-A1 | Chroman derivatives | BAYER HEALTHCARE AG (DE) | 2005-10-06 | — | — | US | disclosed |
| US-20050090398-A1 | Novel tetrazole derivative useful as herbicides | YANAGI AKIHIKO (JP) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222247-A1 | Chroman derivatives | CHRM3, CHRNB3, ADRB3 | ALDH1A1 1115/4885MAPK1 1288/4885HTT 2335/4885 |
| US-20050090398-A1 | Novel tetrazole derivative useful as herbicides | DDT, TTI1, CYP1A1 | ALDH1A1 533/4885MAPK1 2914/4885HTT 616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.