SCHEMBL6491693

SCHEMBL6491693

CCCCc1cn(-c2c(Cl)cccc2OC)c(=O)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 7/20 0.47
AGTR2 P50052 7/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6492623 0.98 AGTR1 (0.45) AGTR1AGTR2
SCHEMBL6492945 0.95 AGTR1 (0.41) AGTR1AGTR2
SCHEMBL6499022 0.95 AGTR1 (0.49) AGTR1AGTR2
SCHEMBL6498565 0.93 AGTR1 (0.47) AGTR1AGTR2
SCHEMBL6492268 0.93 AGTR1 (0.51) AGTR1AGTR2
SCHEMBL8117680 0.93 AGTR1 (0.41) AGTR1AGTR2
SCHEMBL6503500 0.92 AGTR1 (0.52) AGTR1AGTR2
SCHEMBL6494698 0.92 AGTR1 (0.51) AGTR1AGTR2
SCHEMBL8117911 0.92 AGTR1 (0.41) AGTR1AGTR2
SCHEMBL6492671 0.92 AGTR1 (0.46) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344318-A Dynamic dehydration method of 3,3', 4' -biphenyl tetracarboxylic acid 河北海力恒远新材料股份有限公司 2024-07-16 CN claimed
CN-118265745-A Polyimide film, high-frequency circuit board, and flexible electronic device board UBE株式会社 2024-06-28 CN claimed
CN-115745782-B Preparation method and production method of phthalic acid derivative 江西凌富生物科技有限公司 2024-06-07 CN claimed
CN-115521280-B Method for preparing 3,3', 4' -biphenyl tetracarboxylic acid and dianhydride thereof and obtained product 中国石油化工股份有限公司 2024-03-26 CN claimed
CN-117624595-A Method for preparing polyamide acid slurry with high solid content and low viscosity 苏州科丽尔化学有限公司 2024-03-01 CN claimed
CN-117050042-A Preparation method of 3,3', 4' -biphenyl tetracarboxylic dianhydride 上海固创化工新材料有限公司 2023-11-14 CN claimed
CN-116730631-A Polyimide laminate and method for producing same 中化学科学技术研究有限公司 2023-09-12 CN claimed
CN-114854011-B Polyamide acid solution, polyimide film and preparation method thereof 中化学科学技术研究有限公司 2023-08-18 CN claimed
CN-114096508-B Preparation method of 3,3', 4' -dicyclohexyl tetracarboxylic acid and treatment method of acid wastewater 河北海力恒远新材料股份有限公司 2023-08-15 CN claimed
CN-114507130-B Purification method of 3,3', 4' -biphenyl tetracarboxylic acid 河北海力恒远新材料股份有限公司 2023-07-14 CN claimed
CN-113717136-B Synthesis method of 3,3', 4' -biphenyl tetracarboxylic dianhydride 江西师范大学 2023-05-09 CN claimed
CN-114315555-B Synthetic method of 3,3', 4' -biphenyltetracarboxylic acid 河北海力恒远新材料股份有限公司 2023-03-28 CN claimed
CN-115745782-A Preparation method and production method of phthalic acid derivative 江西凌富生物科技有限公司 2023-03-07 CN claimed
CN-115521280-A Method for preparing 3,3', 4' -biphenyl tetracarboxylic acid and dianhydride thereof and obtained product 中国石油化工股份有限公司 2022-12-27 CN claimed
CN-115368566-A Polyimide composite membrane with low moisture absorption rate and low thermal expansion coefficient, preparation method thereof, thermosetting polyamic acid and thermosetting polyamic acid solution 中国科学技术大学先进技术研究院 2022-11-22 CN claimed
US-20040048911-A1 1-phenyl imidazol-2-one biphenylmethyl compounds for treatment of circulatory disorders G. D. SEARLE & CO. 2004-03-11 US claimed
US-20020038035-A1 1-phenyl imidazol-2-one biphenylmethyl compounds for treatment of circulatory disorders G.D. SEARLE & CO. 2002-03-28 US claimed
EP-0690854-B1 1-PHENYL-IMIDAZOL-2-ONE BIPHENYLMETHYL COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS SEARLE & CO (US) 2000-07-12 EP claimed
EP-0978515-A2 1-(substituted phenyl)-4-biphenylmethyl-imidazol-2-one derivatives, their preparation and their use as angiotensin II antagonists G.D. SEARLE & CO. (US) 2000-02-09 EP claimed
WO-1994021629-A1 1-PHENYL-IMIDAZOL-2-ONE BIPHENYLMETHYL COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS G.D. SEARLE & CO. (US) 1994-09-29 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020038035-A1 1-phenyl imidazol-2-one biphenylmethyl compounds for treatment of circulatory disorders AGTR1, AGTR2, REN AGTR1 1/4885AGTR2 2/4885
US-20040048911-A1 1-phenyl imidazol-2-one biphenylmethyl compounds for treatment of circulatory disorders AGTR1, AGTR2, REN AGTR1 1/4885AGTR2 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.