Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL28641628 | 0.95 | MAPK1 (0.31) | — | |
| Guanidine SCHEMBL2126460 | 0.88 | — | — | |
| Guanidine SCHEMBL29983942 | 0.82 | — | — | |
| Guanidine SCHEMBL165720 | 0.82 | NOS2 (0.42) | — | |
| Guanidine SCHEMBL5613752 | 0.82 | — | — | |
| Guanidine SCHEMBL11330173 | 0.82 | — | — | |
| Guanidine SCHEMBL2003 | 0.82 | — | — | |
| Guanidine SCHEMBL25310528 | 0.76 | — | — | |
| Guanidine SCHEMBL19610646 | 0.76 | NOS2 (0.39) | — | |
| Guanidine SCHEMBL66976 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4601992-A | Product and process for the production of granules of high mechanical strength and containing molecular sieve | KALI-CHEMIE AKTIENGESELLSCHAFT (DE) | 1986-07-22 | — | — | US | claimed |
| EP-0071897-B1 | LIGHT-WEIGHT BUILDING MATERIAL AND METHOD FOR ITS PRODUCTION | OTAVI MINEN AG (DE) | 1985-10-16 | — | — | EP | claimed |
| US-4486553-A | HYDROPHILIC EPOXIDE | ODENWALD-CHEMIE GMBH (DE) | 1984-12-04 | — | — | US | claimed |
| EP-0003752-B1 | PROCESS FOR PREPARING MOLECULAR-SIEVE-CONTAINING GRAINS HAVING GOOD MECHANICAL SOLIDITY, THE GRAINS MANUFACTURED BY THIS PROCESS AND THEIR USE | Kali-Chemie Aktiengesellschaft (DE) | 1981-03-18 | — | — | EP | claimed |
| US-3968302-A | Mold release composition containing tungsten disulfide | BALL BROTHERS RESEARCH CORPORATION (US) | 1976-07-06 | — | — | US | claimed |
| US-3947502-A | Production of finely divided acicular magnetic iron oxides | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-30 | — | — | US | claimed |
| JP-9227870-A | — | — | None | — | — | JP | disclosed |
| US-12491493-B1 | Amine appended bimetallic metal-organic framework (MOF-74) for carbon dioxide capture and method of preparation thereof | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2025-12-09 | — | — | US | disclosed |
| US-12489117-B2 | Nonaqueous electrolyte secondary battery | HONDA MOTOR CO., LTD. (JP) | 2025-12-02 | — | — | US | disclosed |
| US-20250158069-A1 | BINDER FOR LITHIUM ION BATTERIES, AND ELECTRODE AND SEPARATOR USING SAME | ATTACCATO LIMITED LIABILITY COMPANY (JP) | 2025-05-15 | — | — | US | disclosed |
| CN-114843490-B | Negative electrode for nonaqueous electrolyte secondary battery and nonaqueous electrolyte secondary battery provided with same | 本田技研工业株式会社 | 2025-02-14 | — | — | CN | disclosed |
| US-20250011241-A1 | GEOPOLYMER COMPOSITIONS INCLUDING ORGANIC BASES AND METHODS OF SYNTHESIZING AND FORMING CERAMICS THEREFROM | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2025-01-09 | — | — | US | disclosed |
| CN-114824166-B | Negative electrode for nonaqueous electrolyte secondary battery and nonaqueous electrolyte secondary battery | 本田技研工业株式会社 | 2024-10-29 | — | — | CN | disclosed |
| US-4039337-A | Release coating for glass manufacture | BALL BROTHERS RESEARCH CORPORATION (US) | 1977-08-02 | — | — | US | disclosed |
| US-3971665-A | SILICA SOL OR SILICATE, QUATERNARY AMMONIUM HYDROXIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JA) | 1976-07-27 | — | — | US | disclosed |
| US-3968302-A | Mold release composition containing tungsten disulfide | BALL BROTHERS RESEARCH CORPORATION (US) | 1976-07-06 | — | — | US | disclosed |
| US-3951838-A | Silica sol stabilizers for improving the stability of sodium percarbonate in solid bleaches and detergents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-04-20 | — | — | US | disclosed |
| US-3947502-A | Production of finely divided acicular magnetic iron oxides | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-30 | — | — | US | disclosed |
| US-3933706-A | SILICATE, VINYL POLYMER EMULSION | KANSAI PAINT COMPANY, LTD. (JA) | 1976-01-20 | — | — | US | disclosed |
| US-3930876-A | SILICATE | MATSUSHITA ELECTRIC WORKS, LTD. (JA) | 1976-01-06 | — | — | US | disclosed |