Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.61 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4910235 | 0.82 | CTSK (0.66) | CTSKCTSLCTSSACACB | |
| SCHEMBL6492755 | 0.80 | CTSK (0.66) | CTSKCTSLCTSS | |
| SCHEMBL4905765 | 0.78 | CTSK (0.65) | CTSKCTSLCTSSACACB | |
| SCHEMBL4907528 | 0.77 | CTSK (0.61) | CTSKCTSLCTSSACHEACACB | |
| SCHEMBL6646844 | 0.76 | CTSK (0.65) | CTSKCTSLCTSSACHEACACB | |
| SCHEMBL4910175 | 0.76 | CTSK (0.66) | CTSKACACB | |
| SCHEMBL14260267 | 0.76 | CTSK (1.00) | CTSKCTSLCTSS | |
| SCHEMBL6646848 | 0.75 | CTSK (0.63) | CTSKCTSLCTSSACHEACACB | |
| SCHEMBL6646902 | 0.75 | CTSK (0.66) | CTSKCTSLCTSS | |
| SCHEMBL4910220 | 0.74 | CTSK (0.73) | CTSKCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050054819-A1 | Cycloalkyl ketoamides derivatives useful as cathepsin k inhibitors | SMITHKLINE BEECHAM CORPORATION | 2005-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050054819-A1 | Cycloalkyl ketoamides derivatives useful as cathepsin k inhibitors | CTSK, CTSS, CTSE | CTSK 1/4885CTSL 12/4885CTSS 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.