Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11504772 | 0.84 | KDM4E (0.45) | KDM4EL3MBTL1RXFP1KDM1APOLB | |
| SCHEMBL11741694 | 0.82 | KDM4E (0.44) | KDM4EL3MBTL1RXFP1KDM1APOLB | |
| SCHEMBL8857146 | 0.82 | SLC6A2 (0.49) | KDM4EL3MBTL1RXFP1KDM1APOLB | |
| SCHEMBL8632555 | 0.82 | ALDH1A1 (0.41) | KDM4EL3MBTL1SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL8852755 | 0.81 | KDM4E (0.44) | KDM4EL3MBTL1RXFP1KDM1APOLB | |
| SCHEMBL11675414 | 0.81 | KDM4E (0.42) | KDM4EL3MBTL1RXFP1KDM1APOLB | |
| SCHEMBL12932623 | 0.81 | AOC3 (0.55) | KDM4EL3MBTL1RXFP1KDM1APOLB | |
| SCHEMBL11701688 | 0.81 | AOC3 (0.44) | KDM4EL3MBTL1RXFP1KDM1APOLB | |
| SCHEMBL9100854 | 0.80 | CETP (0.45) | KDM4EL3MBTL1AOC3SLC6A2SLC6A4 | |
| SCHEMBL17453164 | 0.79 | MMP12 (0.42) | KDM4EL3MBTL1RXFP1KDM1APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12257330-B2 | Hair coloring compositions and methods of use | L'OREAL (FR) | 2025-03-25 | — | — | US | disclosed |
| WO-2005003140-A1 | 4-OXO-4,7-DIHYDROTHIENO[2,3-B]PYRIDINE-5-CARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-01-13 | — | — | WO | disclosed |
| US-20050004161-A1 | 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides as antiviral agents | AGOURON PHARMACEUTICALS, INC. | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004161-A1 | 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides as antiviral agents | ZC3HAV1, IRF3, BRD4 | KDM4E 40/4885L3MBTL1 1342/4885RXFP1 2452/4885 |
| US-12257330-B2 | Hair coloring compositions and methods of use | SGMS1, PHOSPHO1, SGMS2 | KDM4E 3783/4885L3MBTL1 4412/4885RXFP1 4792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.