SCHEMBL64932

SCHEMBL64932

Cc1cc(Cl)c(O)c(Cl)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.58
HSD17B10 Q99714 4/20 0.58
TSHR P16473 3/20 0.58
TTR P02766 2/20 0.58
RECQL P46063 2/20 0.58
CYP3A4 P08684 1/20 0.58
THRB P10828 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.50
SELL P14151 1/20 0.50
SELP P16109 1/20 0.50
SELE P16581 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
ALOX15 P16050 1/20 0.50
ALOX12 P18054 1/20 0.50
CYP2C19 P33261 1/20 0.50
HIF1A Q16665 1/20 0.50
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
HPGD P15428 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8990158 0.86 HSD17B10 (0.43) ALDH1A1HSD17B10TSHRTTRRECQL
SCHEMBL6841589 0.86 SELL (0.65) ALDH1A1HSD17B10TSHRTTRRECQL
SCHEMBL4396495 0.86 ALDH1A1 (0.52) ALDH1A1HSD17B10TSHRTTRRECQL
SCHEMBL13855810 0.82 SELL (0.46) ALDH1A1HSD17B10TSHRTTRRECQL
SCHEMBL10922054 0.82 TSHR (0.46) ALDH1A1HSD17B10TSHRTTRRECQL
SCHEMBL4544561 0.82 ALDH1A1 (0.60) ALDH1A1HSD17B10TSHRTTRRECQL
Hydrochloric Acid SCHEMBL4968110 0.80 ALDH1A1 (0.58) ALDH1A1HSD17B10TSHRTTRRECQL
Dimethylamine SCHEMBL11150585 0.80 ALDH1A1 (0.46) ALDH1A1HSD17B10TSHRTTRRECQL
SCHEMBL69852 0.80 HSPA5 (0.53) ALDH1A1HSD17B10TSHRTTRRECQL
SCHEMBL11624152 0.80 NPC1 (0.40) ALDH1A1HSD17B10TSHRTTRRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 391 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116063662-A Tungsten-based bi-component catalyst, preparation method and application thereof in ring-opening metathesis polymerization 中国石油化工股份有限公司 2023-05-05 CN claimed
CN-104603176-A Polyester co-phosphonates FRX POLYMERS INC 2015-05-06 CN claimed
US-9024054-B2 Process for production of purified O-(2,6-dichloro-4-methyl-phenyl) O,O-dimethyl phosphorothioate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-05-05 US claimed
EP-2383274-B1 PROCESS FOR PRODUCTION OF PURIFIED O-(2,6-DICHLORO-4-METHYL- PHENYL) O,O-DIMETHYL PHOSPHOROTHIOATE SUMITOMO CHEMICAL CO (JP) 2014-10-01 EP claimed
EP-2383274-A1 PROCESS FOR PRODUCTION OF PURIFIED O-(2,6-DICHLORO-4-METHYL- PHENYL) O,O-DIMETHYL PHOSPHOROTHIOATE Sumitomo Chemical Company, Limited (JP) 2011-11-02 EP claimed
US-20110237818-A1 PROCESS FOR PRODUCTION OF PURIFIED O-(2,6-DICHLORO-4-METHYL-PHENYL) O,O-DIMETHYL PHOSPHOROTHIOATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-09-29 US claimed
EP-0526651-A1 BRANCHED POLYCARBONATE IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1993-02-10 EP claimed
US-4983758-A Di- and trihalophenyl esters, racemic mixture resolution, esterification of acid or halide with halo phenol, racemization of optically active ester SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-01-08 US claimed
EP-0012939-B1 PROCESS FOR THE PRODUCTION OF 4-HYDROXYBENZALDEHYDE DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-01-26 EP claimed
US-4351969-A Preparation of chlorophenols RHONE-POULENC INDUSTRIES (FR) 1982-09-28 US claimed
EP-0012939-A1 Process for the production of 4-hydroxybenzaldehyde derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-07-09 EP claimed
WO-2024202889-A1 PHOTOSENSITIVE COMPOSITION, PATTERN-FORMING METHOD USING SAME, AND TRANSITION METAL CLUSTER COMPOUND 三菱ケミカル株式会社 2024-10-03 WO disclosed
CN-113444086-B Ezh2 inhibitors and uses thereof 达纳-法伯癌症研究所股份有限公司 2024-04-30 CN disclosed
CN-117186284-A Method for preparing trans-polyocten (TOR) rubber by tungsten-based bi-component catalyst 华东理工大学 2023-12-08 CN disclosed
CN-117120548-A Polycarbonate resin composition and molded article 出光兴产株式会社 2023-11-24 CN disclosed
US-4351969-A Preparation of chlorophenols RHONE-POULENC INDUSTRIES (FR) 1982-09-28 US disclosed
EP-0012939-A1 Process for the production of 4-hydroxybenzaldehyde derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-07-09 EP disclosed
US-4172932-A Process for the preparation of polymers of cyclopentene or copolymers of cyclopentene with unsaturated alicyclic compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1979-10-30 US disclosed
US-4060468-A TUNGSTEN CONTAINING THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-11-29 US disclosed
US-4039635-A Soil fungicidal phosphorothioate SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-08-02 US disclosed